日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An integrated in vitro human iPSCs-derived neuron and in vivo animal approach for preclinical screening of anti-seizure compounds

综合体外人类 iPSC 衍生神经元和体内动物方法,用于抗癫痫化合物的临床前筛选

Chunfang Zhao, Ben Rollo, Muhammad Shahid Javaid, Ziyu Huang, Wen He, Hong Xu, Patrick Kwan, Chunbo Zhang

Novel CDKL5 targets identified in human iPSC-derived neurons

在人类 iPSC 衍生的神经元中发现新的 CDKL5 靶点

Sean Massey, Ching-Seng Ang, Nadia M Davidson, Anita Quigley, Ben Rollo, Alexander R Harris, Robert M I Kapsa, John Christodoulou #, Nicole J Van Bergen #5

Distinctive In Vitro Phenotypes in iPSC-Derived Neurons From Patients With Gain- and Loss-of-Function SCN2A Developmental and Epileptic Encephalopathy

患有 SCN2A 功能获得和丧失的发育性癫痫性脑病患者的 iPSC 衍生神经元具有独特的体外表型

Miaomiao Mao, Cristiana Mattei, Ben Rollo, Sean Byars, Claire Cuddy, Geza Berecki, Jacqueline Heighway, Svenja Pachernegg, Trevelyan Menheniott, Danielle Apted, Linghan Jia, Kelley Dalby, Alex Nemiroff, Saul Mullen, Christopher A Reid, Snezana Maljevic, Steven Petrou

REST and RCOR genes display distinct expression profiles in neurons and astrocytes using 2D and 3D human pluripotent stem cell models

使用 2D 和 3D 人类多能干细胞模型,REST 和 RCOR 基因在神经元和星形胶质细胞中显示出不同的表达谱

Simon Maksour, Neville Ng, Amy J Hulme, Sara Miellet, Martin Engel, Sonia Sanz Muñoz, Rachelle Balez, Ben Rollo, Rocio K Finol-Urdaneta, Lezanne Ooi, Mirella Dottori

In vitro neurons learn and exhibit sentience when embodied in a simulated game-world

体外神经元在模拟游戏世界中学习并表现出感知能力

Brett J Kagan, Andy C Kitchen, Nhi T Tran, Forough Habibollahi, Moein Khajehnejad, Bradyn J Parker, Anjali Bhat, Ben Rollo, Adeel Razi, Karl J Friston

Antisense oligonucleotide therapy for KCNT1 encephalopathy

反义寡核苷酸治疗 KCNT1 脑病

Lisseth Estefania Burbano, Melody Li, Nikola Jancovski, Paymaan Jafar-Nejad, Kay Richards, Alicia Sedo, Armand Soriano, Ben Rollo, Linghan Jia, Elena V Gazina, Sandra Piltz, Fatwa Adikusuma, Paul Q Thomas, Helen Kopsidas, Frank Rigo, Christopher A Reid, Snezana Maljevic, Steven Petrou

Antisense oligonucleotide therapy reduces seizures and extends life span in an SCN2A gain-of-function epilepsy model

反义寡核苷酸疗法可减少 SCN2A 功能获得性癫痫模型中的癫痫发作并延长寿命

Melody Li, Nikola Jancovski, Paymaan Jafar-Nejad, Lisseth E Burbano, Ben Rollo, Kay Richards, Lisa Drew, Alicia Sedo, Jacqueline Heighway, Svenja Pachernegg, Armand Soriano, Linghan Jia, Todd Blackburn, Blaine Roberts, Alex Nemiroff, Kelley Dalby, Snezana Maljevic, Christopher A Reid, Frank Rigo, St

Multipotent caudal neural progenitors derived from human pluripotent stem cells that give rise to lineages of the central and peripheral nervous system

源自人类多能干细胞的多能尾神经祖细胞,可产生中枢和周围神经系统谱系

Mark Denham, Kouichi Hasegawa, Trevelyan Menheniott, Ben Rollo, Dongcheng Zhang, Shelley Hough, Abdullah Alshawaf, Fabia Febbraro, Samiramis Ighaniyan, Jessie Leung, David A Elliott, Donald F Newgreen, Martin F Pera, Mirella Dottori