Liposome-siRNA-peptide complexes cross the blood-brain barrier and significantly decrease PrP on neuronal cells and PrP in infected cell cultures
脂质体-siRNA-肽复合物能够穿过血脑屏障,并显著降低神经元细胞上的PrP和感染细胞培养物中的PrP。
期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0011085
Pulford, Bruce; Reim, Natalia; Bell, Aimee; Veatch, Jessica; Forster, Genevieve; Bender, Heather; Meyerett, Crystal; Hafeman, Scott; Michel, Brady; Johnson, Theodore; Wyckoff, A Christy; Miele, Gino; Julius, Christian; Kranich, Jan; Schenkel, Alan; Dow, Steven; Zabel, Mark D
血脑屏障
炎症/感染
神经科学
Cell Culture
细胞生物学