Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease
小分子抑制剂直接靶向 CARD9 并模仿其在炎症性肠病中的保护性变体
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:
doi:10.1073/pnas.1705748114
Elizaveta S Leshchiner, Jason S Rush, Michael A Durney, Zhifang Cao, Vlado Dančík, Benjamin Chittick, Huixian Wu, Adam Petrone, Joshua A Bittker, Andrew Phillips, Jose R Perez, Alykhan F Shamji, Virendar K Kaushik, Mark J Daly, Daniel B Graham, Stuart L Schreiber, Ramnik J Xavier