日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds for triggering effector function

抗B7H3 CAR-T构建体的功能亲和力可预测触发效应功能的抗原密度阈值

Marta Barisa ,Henrike P Muller # ,Elisa Zappa # ,Rivani Shah ,Juliane L Buhl ,Benjamin Draper ,Courtney Himsworth ,Chantelle Bowers ,Sophie Munnings-Tomes ,Marilena Nicolaidou ,Sonia Morlando ,Kathleen Birley ,Clara Leboreiro-Babe ,Alice Vitali ,Laura Privitera ,Kyle O'Sullivan ,Ailsa Greppi ,Magdalena Buschhaus ,Mario Barrera Román ,Sam de Blank ,Femke van den Ham ,Brenna R van 't Veld ,Gabrielle Ferry ,Jonathan Fisher ,Debarati Shome ,Reza Nadafi ,Israrul H Ansari ,Rogier Reijmers ,Stefano Giuliani ,Paul Sondel ,Laura K Donovan ,Louis Chesler ,Jan Molenaar ,Jarno Drost ,Anne C Rios ,Kerry Chester ,Judith Wienke ,John Anderson

Protocol for preclinical evaluation of locoregionally delivered CAR T cells in patient-derived xenograft models of brain tumors

用于在患者来源的脑肿瘤异种移植模型中对局部递送的CAR T细胞进行临床前评估的方案

Benjamin Draper,Chantelle Bowers,Eleni Vassalou,Ailsa Greppi,John Anderson,Nabil Ahmed,Michael D Taylor,Laura K Donovan

Quantitative analysis of preferential utilization of AAV ITR as the packaging terminal signal

优先利用AAV ITR作为包装末端信号的定量分析

Xin Li #, Lohra Mickelle Miller #, Matthew Chrzanowski, Jiahe Tian, Martin F Jarrold, Roland W Herzog, Weidong Xiao, Benjamin Draper, Junping Zhang

Generation of human parallel chimeric antigen receptor (pCAR) T cells to achieve synergistic T cell co-stimulation

构建人类平行嵌合抗原受体(pCAR)T细胞以实现协同T细胞共刺激

Daniel Larcombe-Young,Lynsey Whilding,David Marc Davies,Benjamin Draper,Natasha Bechman,John Maher

TGF-β1 potentiates Vγ9Vδ2 T cell adoptive immunotherapy of cancer

TGF-β1增强Vγ9Vδ2 T细胞过继免疫疗法治疗癌症的作用。

Richard E Beatson,Ana C Parente-Pereira,Leena Halim,Domenico Cozzetto,Caroline Hull,Lynsey M Whilding,Olivier Martinez,Chelsea A Taylor,Jana Obajdin,Kim Ngan Luu Hoang,Benjamin Draper,Ayesha Iqbal,Tom Hardiman,Tomasz Zabinski,Francis Man,Rafael T M de Rosales,Jinger Xie,Fred Aswad,Daniela Achkova,Chung-Yang Ricardo Joseph,Sara Ciprut,Antonella Adami,Helge G Roider,Holger Hess-Stumpp,Balázs Győrffy,Jelmar Quist,Anita Grigoriadis,Anette Sommer,Andrew N J Tutt,David M Davies,John Maher

Synergistic T cell signaling by 41BB and CD28 is optimally achieved by membrane proximal positioning within parallel chimeric antigen receptors

41BB 和 CD28 协同 T 细胞信号传导的最佳实现方式是它们在平行嵌合抗原受体中位于细胞膜附近。

Tamara Muliaditan,Leena Halim,Lynsey M Whilding,Benjamin Draper,Daniela Y Achkova,Fahima Kausar,Maya Glover,Natasha Bechman,Appitha Arulappu,Jenifer Sanchez,Katie R Flaherty,Jana Obajdin,Kristiana Grigoriadis,Pierre Antoine,Daniel Larcombe-Young,Caroline M Hull,Richard Buus,Peter Gordon,Anita Grigoriadis,David M Davies,Anna Schurich,John Maher

In Vivo PET Tracking of 89Zr-Labeled Vγ9Vδ2 T Cells to Mouse Xenograft Breast Tumors Activated with Liposomal Alendronate

利用 89Zr 标记的 Vγ9Vδ2 T 细胞在脂质体阿仑膦酸钠激活的小鼠异种移植乳腺肿瘤中的体内 PET 追踪

Francis Man ,Lindsay Lim ,Alessia Volpe ,Alberto Gabizon ,Hilary Shmeeda ,Benjamin Draper ,Ana C Parente-Pereira ,John Maher ,Philip J Blower ,Gilbert O Fruhwirth ,Rafael T M de Rosales

CAR T-Cells Targeting the Integrin αvβ6 and Co-Expressing the Chemokine Receptor CXCR2 Demonstrate Enhanced Homing and Efficacy against Several Solid Malignancies

靶向整合素 αvβ6 并共同表达趋化因子受体 CXCR2 的 CAR-T 细胞表现出增强的归巢能力和对抗多种实体恶性肿瘤的疗效

Lynsey M Whilding, Leena Halim, Benjamin Draper, Ana C Parente-Pereira, Tomasz Zabinski, David Marc Davies, John Maher