日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mapping cellular targets of covalent cancer drugs in the entire mammalian body.

绘制共价抗癌药物在哺乳动物体内的细胞靶点图谱。

Pang Zhengyuan, Leung Verina H, Wang Cailynn C, Attarpour Ahmadreza, Rinaldi Anthony, Shen Hanbing, Moya-Garzon Maria Dolores, Sigua Logan H, Rammel Claire, Selke Alexandra, Glynn Christopher, Yender Melaina, Xu Senhan, Moslehi Javid J, Wu Peng, Long Jonathan Z, Goubran Maged, Cravatt Benjamin F, Ye Li

Cryo-EM structures of higher order Gephyrin oligomers reveal principles of inhibitory postsynaptic scaffold organization

高级Gephyrin寡聚体的冷冻电镜结构揭示了抑制性突触后支架组织的原理

Ortiz-López, Diego; Hove, Tamsanqa T; Huhn, Christiane; Camuso, Serena; van Gen Hassend, Pia M; Sander, Bodo; Campbell, Benjamin F N; Tyagarajan, Shiva K; Plückthun, Andreas; Specht, Christian G; Maric, Hans M; Böttcher, Bettina; Schindelin, Hermann

Cutaneous lupus damage is negatively predicted by disease subtype and systemic involvement and is associated with worse outcomes in body image: A prospective cohort study

皮肤狼疮损伤与疾病亚型和系统受累呈负相关,且与较差的身体形象相关:一项前瞻性队列研究

Cepica, Tyler B; Lu, Grace; Xie, Lillian; Faden, Daniella F; Stone, Caroline J; Chambers, Shae; Feng, Rui; Werth, Victoria P; Chong, Benjamin F

A Randomized, Placebo-Controlled Trial of Hydroxychloroquine in Incomplete Lupus

羟氯喹治疗不完全性红斑狼疮的随机、安慰剂对照试验

Olsen, Nancy J; Liao, Duanping; James, Judith A; Guthridge, Joel M; Arriens, Cristina; Kamen, Diane; Ishimori, Mariko; Wallace, Daniel J; Striebich, Christopher; Narain, Sonali; Chong, Benjamin F; He, Fan; Schaefer, Eric W; Chinchilli, Vernon M; Karp, David R

Integrated phenotypic screening and chemical proteomics identifies ETF1 ligands that modulate viral translation and replication.

整合表型筛选和化学蛋白质组学鉴定出调节病毒翻译和复制的 ETF1 配体。

Kim Arthur S, Ma Kevin, Reinhardt Christopher J, Lazar Daniel C, Ogasawara Daisuke, Shaw Teressa M, de la Torre Juan Carlos, Bailey Adam L, Melillo Bruno, Teijaro John R, Cravatt Benjamin F

Structural and mechanistic analysis of covalent ligands targeting the RNA-binding protein NONO.

针对 RNA 结合蛋白 NONO 的共价配体的结构和机制分析。

Lindsey Garrett L, Hockley Thomas K, Gomez Alejandro Villa, Marshall Andrew C, Brothers William R, Finney Colin T, Gross Jacob, Fox Archa H, Yeo Gene W, Melillo Bruno, Bond Charles S, Cravatt Benjamin F

EGFR-mutant transformed small cell lung cancer harbors intratumoral heterogeneity targetable with MEK inhibitor combination therapy.

EGFR突变型小细胞肺癌具有肿瘤内异质性,可通过MEK抑制剂联合疗法进行靶向治疗。

Ogino Atsuko, Vajdi Amir, Mu Xinmeng Jasmine, Mahadevan Navin R, Ngo Kenneth, Booker Matthew A, Cejas Paloma, Okoro Jeffrey J, Xu Man, Springer Benjamin F, Eschle Benjamin K, Messier Cameron M, Wang Stephen, Syamala Sudeepa, Tamen Rubii M, Adeni Anika E, Chambers Emily S, Canadas Israel, Thai Tran, Christensen Camilla L, Xu Chunxiao, Lizotte Patrick H, Oxnard Geoffrey R, Watanabe Hideo, Long Henry W, Gokhale Prafulla C, Paweletz Cloud P, Sholl Lynette M, Oser Matthew G, Barbie David A, Tolstorukov Michael Y, Jänne Pasi A

Intraminority Body Stigma and Body Dissatisfaction Clarify the Prospective Link Between LGBTQ+ Community Involvement and Thinness-Oriented Disordered Eating in Sexual Minoritized Men

少数群体内部的身体污名和身体不满阐明了 LGBTQ+ 社群参与和性少数男性以瘦为导向的饮食失调之间的潜在联系

Barnhart, Wesley R; Shepherd, Benjamin F; Dixit, Urvashi; Costello, Kayla; Convertino, Alexandra D; Brown, Tiffany; Braden, Abby; Nagata, Jason M; He, Jinbo

A Machine Learning-Based Dynamic SST Index for Long-Lead Malaria Prediction in the Peruvian Amazon

基于机器学习的动态海表温度指数用于秘鲁亚马逊地区疟疾的长期预测

Pan, Mengxin; Hu, Shineng; Janko, Mark M; Zaitchik, Benjamin F; Takahashi, Ken; Lescano, Andres G; Munayco, Cesar V; Pan, William K

Indirect benefits of seasonal malaria chemoprevention for non-malarial pediatric infections and routine antibiotic use in real-world programmatic settings: a pre-post study using positive and negative controls

在真实世界项目环境中,季节性疟疾化学预防对非疟疾性儿科感染和常规抗生素使用的间接益处:一项采用阳性和阴性对照的前后对照研究

Gebreegziabher, Elisabeth A; Ouattara, Mamadou; Bountogo, Mamadou; Coulibaly, Boubacar; Boudo, Valentin; Ouedraogo, Thierry; Lebas, Elodie; Hu, Huiyu; O'Brien, Kieran S; Hsiang, Michelle S; Glidden, David V; Arnold, Benjamin F; Lietman, Thomas M; Sié, Ali; Oldenburg, Catherine E