Overcoming Acquired Resistance to AZD9291, A Third-Generation EGFR Inhibitor, through Modulation of MEK/ERK-Dependent Bim and Mcl-1 Degradation
通过调节 MEK/ERK 依赖的 Bim 和 Mcl-1 降解克服对第三代 EGFR 抑制剂 AZD9291 的获得性耐药性
期刊:Clinical Cancer Research
影响因子:10
doi:10.1158/1078-0432.CCR-17-1574
Puyu Shi, You-Take Oh, Liang Deng, Guojing Zhang, Guoqing Qian, Shuo Zhang, Hui Ren, Grant Wu, Benjamin Legendre Jr, Emily Anderson, Suresh S Ramalingam, Taofeek K Owonikoko, Mingwei Chen, Shi-Yong Sun
