文献库，生知库 | 链接生命科学的每一步

日期影响因子

Structural rearrangements in the nucleus localize latent HIV proviruses to a perinucleolar compartment supportive of reactivation

细胞核内的结构重排将潜伏的 HIV 原病毒定位到支持重新激活的核仁周围区室

期刊:Proceedings of the National Academy of Sciences of the United States of America

doi:10.1073/pnas.2202003121

Fredrick Kizito, Kien Nguyen, Uri Mbonye, Meenakshi Shukla, Benjamin Luttge, Mary Ann Checkley, Anna Agaponova, Konstantin Leskov, Jonathan Karn

发表日期：2024

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Reduced and highly diverse peripheral HIV-1 reservoir in virally suppressed patients infected with non-B HIV-1 strains in Uganda

乌干达感染非 B 型 HIV-1 毒株且病毒受到抑制的患者外周 HIV-1 宿主减少且高度多样化

期刊:Retrovirology

影响因子:2.7

doi:10.1186/s12977-022-00587-3

Samira Joussef-Piña, Immaculate Nankya, Sophie Nalukwago, Joy Baseke, Sandra Rwambuya, Dane Winner, Fred Kyeyune, Keith Chervenak, Bonnie Thiel, Robert Asaad, Curtis Dobrowolski, Benjamin Luttge, Blair Lawley, Cissy M Kityo, W Henry Boom, Jonathan Karn, Miguel E Quiñones-Mateu

发表日期：2022

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Inhibition of the H3K27 demethylase UTX enhances the epigenetic silencing of HIV proviruses and induces HIV-1 DNA hypermethylation but fails to permanently block HIV reactivation

抑制 H3K27 去甲基化酶 UTX 可增强 HIV 原病毒的表观遗传沉默，并诱导 HIV-1 DNA 高甲基化，但无法永久阻止 HIV 再激活

期刊:PLoS Pathogens

影响因子:5.5

doi:10.1371/journal.ppat.1010014

Kien Nguyen, Curtis Dobrowolski, Meenakshi Shukla, Won-Kyung Cho, Benjamin Luttge, Jonathan Karn

发表日期：2021

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Estrogen receptor-1 is a key regulator of HIV-1 latency that imparts gender-specific restrictions on the latent reservoir

雌激素受体-1 是 HIV-1 潜伏期的关键调节因子，可对潜伏期病毒库施加性别特异性限制

期刊:Proceedings of the National Academy of Sciences of the United States of America

doi:10.1073/pnas.1803468115

Biswajit Das, Curtis Dobrowolski, Benjamin Luttge, Saba Valadkhan, Nicolas Chomont, Rowena Johnston, Peter Bacchetti, Rebecca Hoh, Monica Gandhi, Steven G Deeks, Eileen Scully, Jonathan Karn

发表日期：2018

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Immortalization of primary microglia: a new platform to study HIV regulation in the central nervous system

原代小胶质细胞永生化：研究中枢神经系统中HIV调控的新平台

期刊:Journal of Neurovirology

影响因子:2.3

doi:10.1007/s13365-016-0499-3

Yoelvis Garcia-Mesa ，Taylor R Jay ，Mary Ann Checkley ，Benjamin Luttge ，Curtis Dobrowolski ，Saba Valadkhan ，Gary E Landreth ，Jonathan Karn ，David Alvarez-Carbonell

细胞生物学

发表日期：2017

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