Type I but Not Type II Calreticulin Mutations Activate the IRE1α/XBP1 Pathway of the Unfolded Protein Response to Drive Myeloproliferative Neoplasms
型而非 II 型钙网蛋白突变可激活未折叠蛋白反应的 IRE1α/XBP1 通路,从而驱动骨髓增生性肿瘤
期刊:Blood Cancer Discovery
影响因子:11.5
doi:10.1158/2643-3230.BCD-21-0144
Juan Ibarra #, Yassmin A Elbanna #, Katarzyna Kurylowicz, Michele Ciboddo, Harrison S Greenbaum, Nicole S Arellano, Deborah Rodriguez, Maria Evers, Althea Bock-Hughes, Chenyu Liu, Quinn Smith, Julian Lutze, Julian Baumeister, Milena Kalmer, Kathrin Olschok, Benjamin Nicholson, Diane Silva, Luke Maxw