Benjamin P Hurrell相关文献与解析，生知库

Mohammad Hossein Kazemi, Zahra Momeni-Varposhti, Xin Li, Benjamin P Hurrell, Yoshihiro Sakano, Stephen Shen, Pedram Shafiei-Jahani, Kei Sakano, Omid Akbari

免疫

Checkpoint

发表日期：2025

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SIRPα engagement regulates ILC2 effector function and alleviates airway hyperreactivity via modulating energy metabolism

SIRPα 参与调节 ILC2 效应功能并通过调节能量代谢缓解气道高反应性

期刊:Cellular & Molecular Immunology

影响因子:21.8

doi:10.1038/s41423-024-01208-z

Yoshihiro Sakano, Kei Sakano, Benjamin P Hurrell, Pedram Shafiei-Jahani, Mohammad Hossein Kazemi, Xin Li, Stephen Shen, Richard Barbers, Omid Akbari

代谢

发表日期：2024

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Piezo1 channels restrain ILC2s and regulate the development of airway hyperreactivity

Piezo1通道抑制ILC2细胞并调节气道高反应性的发展

期刊:Journal of Experimental Medicine

影响因子:12.6

doi:10.1084/jem.20231835

Benjamin P Hurrell ，Stephen Shen ，Xin Li ，Yoshihiro Sakano ，Mohammad Hossein Kazemi ，Christine Quach ，Pedram Shafiei-Jahani ，Kei Sakano ，Homayon Ghiasi ，Omid Akbari

细胞生物学

发表日期：2024

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CB2 stimulation of adipose resident ILC2s orchestrates immune balance and ameliorates type 2 diabetes mellitus

CB2刺激脂肪组织驻留的ILC2细胞，调节免疫平衡并改善2型糖尿病

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2024.114434

Pedram Shafiei-Jahani ，Shi Yan ，Mohammad H Kazemi ，Xin Li ，Amitis Akbari ，Kei Sakano ，Yoshihiro Sakano ，Benjamin P Hurrell ，Omid Akbari

Hepatitis B virus e antigen induces atypical metabolism and differentially regulates programmed cell deaths of macrophages

乙型肝炎病毒e抗原诱导非典型代谢并对巨噬细胞的程序性细胞死亡进行差异性调节

期刊:PLoS Pathogens

影响因子:5.5

doi:10.1371/journal.ppat.1012079

Yumei Li ，Christine Wu ，Jiyoung Lee ，Qiqi Ning ，Juhyeon Lim ，Hyungjin Eoh ，Sean Wang ，Benjamin P Hurrell ，Omid Akbari ，Jing-Hsiung James Ou

Orai inhibition modulates pulmonary ILC2 metabolism and alleviates airway hyperreactivity in murine and humanized models

Orai 抑制剂可调节肺 ILC2 代谢并缓解小鼠和人源化模型中的气道高反应性

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-023-41065-4

Emily Howard, Benjamin P Hurrell, Doumet Georges Helou, Pedram Shafiei-Jahani, Spyridon Hasiakos, Jacob Painter, Sonal Srikanth, Yousang Gwack, Omid Akbari

代谢

发表日期：2023

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Human PD-1 agonist treatment alleviates neutrophilic asthma by reprogramming T cells

人类 PD-1 激动剂治疗通过重编程 T 细胞缓解中性粒细胞哮喘

期刊:Journal of Allergy and Clinical Immunology

影响因子:11.4

doi:10.1016/j.jaci.2022.07.022

Doumet Georges Helou, Christine Quach, Marshall Fung, Jacob D Painter, Benjamin P Hurrell, Yong-Hwee Eddie Loh, Emily Howard, Pedram Shafiei-Jahani, Pejman Soroosh, Arlene H Sharpe, Omid Akbari

PD-L2 controls peripherally induced regulatory T cells by maintaining metabolic activity and Foxp3 stability

PD-L2 通过维持代谢活性和 Foxp3 稳定性来控制外周诱导调节性 T 细胞

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-022-32899-5

Benjamin P Hurrell, Doumet Georges Helou, Emily Howard, Jacob D Painter, Pedram Shafiei-Jahani, Arlene H Sharpe, Omid Akbari

Autophagy impairment in liver CD11c+ cells promotes non-alcoholic fatty liver disease through production of IL-23

肝脏CD11c+细胞自噬功能障碍通过产生IL-23促进非酒精性脂肪肝疾病的发生发展。

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-022-29174-y

Lauriane Galle-Treger # ，Doumet Georges Helou # ，Christine Quach ，Emily Howard ，Benjamin P Hurrell ，German R Aleman Muench ，Pedram Shafiei-Jahani ，Jacob D Painter ，Andrea Iorga ，Lily Dara ，Juliet Emamaullee ，Lucy Golden-Mason ，Hugo R Rosen ，Pejman Soroosh ，Omid Akbari

LAIR-1 acts as an immune checkpoint on activated ILC2s and regulates the induction of airway hyperreactivity

LAIR-1 充当激活的 ILC2 上的免疫检查点，并调节气道高反应性的诱导

期刊:Journal of Allergy and Clinical Immunology

影响因子:11.4

doi:10.1016/j.jaci.2021.05.042

Doumet Georges Helou, Pedram Shafiei-Jahani, Benjamin P Hurrell, Jacob D Painter, Christine Quach, Emily Howard, Omid Akbari

FOXO1 pathway activation by VISTA immune checkpoint restrains pulmonary ILC2 functions

VISTA 免疫检查点激活 FOXO1 通路抑制肺部 ILC2 功能

SIRPα engagement regulates ILC2 effector function and alleviates airway hyperreactivity via modulating energy metabolism

SIRPα 参与调节 ILC2 效应功能并通过调节能量代谢缓解气道高反应性

Piezo1 channels restrain ILC2s and regulate the development of airway hyperreactivity

Piezo1通道抑制ILC2细胞并调节气道高反应性的发展

CB2 stimulation of adipose resident ILC2s orchestrates immune balance and ameliorates type 2 diabetes mellitus

CB2刺激脂肪组织驻留的ILC2细胞，调节免疫平衡并改善2型糖尿病

Hepatitis B virus e antigen induces atypical metabolism and differentially regulates programmed cell deaths of macrophages

乙型肝炎病毒e抗原诱导非典型代谢并对巨噬细胞的程序性细胞死亡进行差异性调节

Orai inhibition modulates pulmonary ILC2 metabolism and alleviates airway hyperreactivity in murine and humanized models

Orai 抑制剂可调节肺 ILC2 代谢并缓解小鼠和人源化模型中的气道高反应性

Human PD-1 agonist treatment alleviates neutrophilic asthma by reprogramming T cells

人类 PD-1 激动剂治疗通过重编程 T 细胞缓解中性粒细胞哮喘

PD-L2 controls peripherally induced regulatory T cells by maintaining metabolic activity and Foxp3 stability

PD-L2 通过维持代谢活性和 Foxp3 稳定性来控制外周诱导调节性 T 细胞

Autophagy impairment in liver CD11c+ cells promotes non-alcoholic fatty liver disease through production of IL-23

肝脏CD11c+细胞自噬功能障碍通过产生IL-23促进非酒精性脂肪肝疾病的发生发展。

LAIR-1 acts as an immune checkpoint on activated ILC2s and regulates the induction of airway hyperreactivity

LAIR-1 充当激活的 ILC2 上的免疫检查点，并调节气道高反应性的诱导