日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors

利用环状单链DNA供体进行高效的同源定向修复

Sukanya Iyer,Aamir Mir,Joel Vega-Badillo,Benjamin P Roscoe,Raed Ibraheim,Lihua Julie Zhu,Jooyoung Lee,Pengpeng Liu,Kevin Luk,Esther Mintzer,Dongsheng Guo,Josias Soares de Brito,Charles P Emerson Jr,Phillip D Zamore,Erik J Sontheimer,Scot A Wolfe

Highly efficient therapeutic gene editing of human hematopoietic stem cells

高效的人类造血干细胞治疗性基因编辑

Yuxuan Wu ,Jing Zeng ,Benjamin P Roscoe ,Pengpeng Liu ,Qiuming Yao ,Cicera R Lazzarotto ,Kendell Clement ,Mitchel A Cole ,Kevin Luk ,Cristina Baricordi ,Anne H Shen ,Chunyan Ren ,Erica B Esrick ,John P Manis ,David M Dorfman ,David A Williams ,Alessandra Biffi ,Carlo Brugnara ,Luca Biasco ,Christian Brendel ,Luca Pinello ,Shengdar Q Tsai ,Scot A Wolfe ,Daniel E Bauer

Precise therapeutic gene correction by a simple nuclease-induced double-stranded break

通过简单的核酸酶诱导的双链断裂进行精确的治疗基因校正

Sukanya Iyer #, Sneha Suresh #, Dongsheng Guo, Katelyn Daman, Jennifer C J Chen, Pengpeng Liu, Marina Zieger, Kevin Luk, Benjamin P Roscoe, Christian Mueller, Oliver D King, Charles P Emerson Jr, Scot A Wolfe

Systematic exploration of ubiquitin sequence, E1 activation efficiency, and experimental fitness in yeast

系统探索酵母中的泛素序列、E1 活化效率和实验适应性

Benjamin P Roscoe, Daniel N A Bolon