Pharmacological inhibition of Polo-like kinase 1 (PLK1) by BI-2536 decreases the viability and survival of hamartin and tuberin deficient cells via induction of apoptosis and attenuation of autophagy
BI-2536 通过药理学抑制 Polo 样激酶 1 (PLK1)，通过诱导细胞凋亡和减弱自噬，降低了 hamartin 和 tuberin 缺乏细胞的活力和存活率
期刊:Cell Cycle
影响因子:3.4
doi:10.4161/15384101.2014.986394
Matthildi Valianou, Andrew M Cox, Benjamin Pichette, Shannon Hartley, Unmesha Roy Paladhi, Aristotelis Astrinidis
信号转导
细胞生物学
其它细胞
WB
Apoptosis
Autophagy
