日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Immune targeting of three independent suppressive pathways (TIGIT, PD-L1, TGFβ) provides significant antitumor efficacy in immune checkpoint resistant models

三种独立抑制通路(TIGIT、PD-L1、TGFβ)的免疫靶向作用在免疫检查点耐药模型中提供了显著的抗肿瘤功效

S Elizabeth Franks, Kellsye P Fabian, Ginette Santiago-Sánchez, Benjamin Wolfson, James W Hodge

Exploiting off-target effects of estrogen deprivation to sensitize estrogen receptor negative breast cancer to immune killing

利用雌激素缺乏的脱靶效应使雌激素受体阴性乳腺癌对免疫杀伤敏感

Benjamin Wolfson, Michelle R Padget, Jeffrey Schlom, James W Hodge

Overcoming hypoxia-induced functional suppression of NK cells

克服缺氧引起的 NK 细胞功能抑制

Kristen Solocinski, Michelle R Padget, Kellsye P Fabian, Benjamin Wolfson, Fabiola Cecchi, Todd Hembrough, Stephen C Benz, Shahrooz Rabizadeh, Patrick Soon-Shiong, Jeffrey Schlom, James W Hodge

Immunotherapy utilizing the combination of natural killer- and antibody dependent cellular cytotoxicity (ADCC)-mediating agents with poly (ADP-ribose) polymerase (PARP) inhibition

免疫疗法利用自然杀伤细胞和抗体依赖性细胞毒性 (ADCC) 介导剂与聚 (ADP-核糖) 聚合酶 (PARP) 抑制剂的组合

Kathleen E Fenerty, Michelle Padget, Benjamin Wolfson, Sofia R Gameiro, Zhen Su, John H Lee, Shahrooz Rabizadeh, Patrick Soon-Shiong, James W Hodge

Tumor-associated myoepithelial cells promote the invasive progression of ductal carcinoma in situ through activation of TGFβ signaling

肿瘤相关肌上皮细胞通过激活TGFβ信号通路促进导管原位癌的侵袭性进展。

Pang-Kuo Lo ,Yongshu Zhang ,Yuan Yao ,Benjamin Wolfson ,Justine Yu ,Shu-Yan Han ,Nadire Duru ,Qun Zhou

A High-Fat Diet Promotes Mammary Gland Myofibroblast Differentiation through MicroRNA 140 Downregulation

高脂饮食通过下调microRNA 140促进乳腺肌成纤维细胞分化

Benjamin Wolfson ,Yongshu Zhang ,Ramkishore Gernapudi ,Nadire Duru ,Yuan Yao ,Pang-Kuo Lo ,Qun Zhou

Loss of miR-140 is a key risk factor for radiation-induced lung fibrosis through reprogramming fibroblasts and macrophages

miR-140 的缺失是导致放射性肺纤维化的关键危险因素,其通过重编程成纤维细胞和巨噬细胞实现

Nadire Duru, Yongshu Zhang, Ramkishore Gernapudi, Benjamin Wolfson, Pang-Kuo Lo, Yuan Yao, Qun Zhou

Characterization of the CD49f+/CD44+/CD24- single-cell derived stem cell population in basal-like DCIS cells

基底样 DCIS 细胞中 CD49f+/CD44+/CD24- 单细胞衍生干细胞群的表征

Nadire Duru, Ramkishore Gernapudi, Pang-Kuo Lo, Yuan Yao, Benjamin Wolfson, Yongshu Zhang, Qun Zhou

Targeting exosomes from preadipocytes inhibits preadipocyte to cancer stem cell signaling in early-stage breast cancer

靶向来自前脂肪细胞的外泌体可抑制早期乳腺癌中前脂肪细胞向癌症干细胞的信号传导

Ramkishore Gernapudi, Yuan Yao, Yongshu Zhang, Benjamin Wolfson, Sanchita Roy, Nadire Duru, Gabriel Eades, Peixin Yang, Qun Zhou