日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Drugging DNA Damage Repair Pathways for Trinucleotide Repeat Expansion Diseases

药物靶向DNA损伤修复通路治疗三核苷酸重复序列扩增疾病

Benn, Caroline L; Gibson, Karl R; Reynolds, David S

Physiology of Hyperuricemia and Urate-Lowering Treatments

高尿酸血症的生理机制及降尿酸治疗

Benn, Caroline L; Dua, Pinky; Gurrell, Rachel; Loudon, Peter; Pike, Andrew; Storer, R Ian; Vangjeli, Ciara

SAHA decreases HDAC 2 and 4 levels in vivo and improves molecular phenotypes in the R6/2 mouse model of Huntington's disease.

SAHA 可降低体内 HDAC 2 和 4 的水平,并改善亨廷顿病 R6/2 小鼠模型的分子表型

Mielcarek Michal, Benn Caroline L, Franklin Sophie A, Smith Donna L, Woodman Ben, Marks Paul A, Bates Gillian P

Genetic knock-down of HDAC7 does not ameliorate disease pathogenesis in the R6/2 mouse model of Huntington's disease.

在亨廷顿病的 R6/2 小鼠模型中,基因敲除 HDAC7 并不能改善疾病的发病机制

Benn Caroline L, Butler Rachel, Mariner Lydia, Nixon Jude, Moffitt Hilary, Mielcarek Michal, Woodman Ben, Bates Gillian P

Optimisation of region-specific reference gene selection and relative gene expression analysis methods for pre-clinical trials of Huntington's disease

针对亨廷顿病临床前试验,优化区域特异性参考基因选择和相对基因表达分析方法

Benn, Caroline L; Fox, Helen; Bates, Gillian P