日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cell-death pathways and tau-associated neuronal vulnerability in Alzheimer's disease.

阿尔茨海默病中的细胞死亡途径和 tau 蛋白相关的神经元脆弱性

Lin Gen, Chancellor Sarah E, Kwon Taekyung, Woodbury Maya E, Doering Astrid, Abdourahman Aicha, Bennett Rachel E, Liao Fan, Pastika Timothy, Tamm Joseph, Romanul Nandini, Yanamandra Kiran, Hu Miwei, Zhao Karen, Frosch Matthew P, Grinberg Yelena, Li Huan, Das Sudeshna, Dellovade Tammy, Karran Eric H, Talanian Robert V, Biber Knut, Serrano-Pozo Alberto, Ried Janina S, Langlois Xavier, Hyman Bradley T

Tau drives cell specific functional isolation of the hippocampal formation

Tau蛋白驱动海马结构细胞特异性功能隔离

Zwang, Theodore J; Zhang, Jasen; Gelb-Bicknell, Rudy; Wolf, Nina; Chanchykov, Viktor; Zhu, Haoyang; Agastra, Ergina; Devine, Ava; Holbrook, Andrew J; Bennett, Rachel E; Hyman, Bradley T

Aberrant vascular architecture in the hippocampus correlates with tau burden in mild cognitive impairment and Alzheimer's disease

海马体血管结构异常与轻度认知障碍和阿尔茨海默病中的tau蛋白负荷相关

Lee, Hansol; Fu, Jessie Fanglu; Gaudet, Kyla; Bryant, Annie G; Price, Julie C; Bennett, Rachel E; Johnson, Keith A; Hyman, Bradley T; Hedden, Trey; Salat, David H; Yen, Yi-Fen; Huang, Susie Y

Molecular profiling of frontal and occipital subcortical white matter hyperintensities in Alzheimer's disease

阿尔茨海默病额叶和枕叶皮质下白质高信号的分子谱分析

Malla, Sulochan; Bryant, Annie G; Jayakumar, Rojashree; Woost, Benjamin; Wolf, Nina; Li, Andrew; Das, Sudeshna; van Veluw, Susanne J; Bennett, Rachel E

Expression-based selection identifies a microglia-tropic AAV capsid for direct and CSF routes of administration in mice

基于表达的筛选鉴定出一种嗜小胶质细胞的AAV衣壳,可用于小鼠的直接给药和脑脊液给药。

Santoscoy, Miguel C; Espinoza, Paula; Hanlon, Killian S; Yang, Luna; Nieland, Lisa; Ng, Carrie; Badr, Christian E; Hickman, Suzanne; de la Cruz, Demitri; Griciuc, Ana; Elkhoury, Joseph; Bennett, Rachel E; Shen, Shiqian; Maguire, Casey A

Heterogeneity of Tau Deposition and Microvascular Involvement in MCI and AD

轻度认知障碍和阿尔茨海默病中Tau蛋白沉积和微血管受累的异质性

Bryant, Annie G; Manhard, Mary K; Salat, David H; Rosen, Bruce R; Hyman, Bradley T; Johnson, Keith A; Huang, Susie; Bennett, Rachel E; Yen, Yi-Fen

PTEN activation contributes to neuronal and synaptic engulfment by microglia in tauopathy

PTEN激活促进tau蛋白病中小胶质细胞对神经元和突触的吞噬。

Benetatos, Joseph; Bennett, Rachel E; Evans, Harrison T; Ellis, Sevannah A; Hyman, Bradley T; Bodea, Liviu-Gabriel; Götz, Jürgen

Synaptic and metabolic gene expression alterations in neurons that are recipients of proteopathic tau seeds

接受蛋白病变tau种子的神经元中突触和代谢基因表达发生改变

Perez-Rando, Marta; Dujardin, Simon; Bennett, Rachel E; Commins, Caitlin; Nibhanupudy, Tara; Hyman, Bradley T

Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease

脑血管衰老与阿尔茨海默病中的tau蛋白病理有关

Bryant, Annie G; Hu, Miwei; Carlyle, Becky C; Arnold, Steven E; Frosch, Matthew P; Das, Sudeshna; Hyman, Bradley T; Bennett, Rachel E

Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo

在β-淀粉样蛋白存在的情况下,tau蛋白的减少可以预防体内tau蛋白病理和神经元死亡。

DeVos, Sarah L; Corjuc, Bianca T; Commins, Caitlin; Dujardin, Simon; Bannon, Riley N; Corjuc, Diana; Moore, Benjamin D; Bennett, Rachel E; Jorfi, Mehdi; Gonzales, Jose A; Dooley, Patrick M; Roe, Allyson D; Pitstick, Rose; Irimia, Daniel; Frosch, Matthew P; Carlson, George A; Hyman, Bradley T