日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

C1q-dependent clearance of alpha-synuclein allows macrophages to transiently limit enteric synucleinopathy in male mice

C1q依赖性α-突触核蛋白清除作用使巨噬细胞能够暂时性地限制雄性小鼠的肠道突触核蛋白病。

Mackie, Phillip M; Koshy, Joanne M; Bhogade, Mauli H; Hammoor, Tristan; Hachmeister, William; Lloyd, Grace M; Paterno, Giavanna; Bolen, Mackenzie L; Merchak, Andrea; Gamez-Tansey, Malu; Giasson, Benoit I; Khoshbouei, Habibeh

Rigorous evaluation of pathological α-synucleinopathy transmissibility between animals in an experimental model

在实验模型中对动物间病理性α-突触核蛋白病的传播性进行严格评估

Sacino, Amanda N; Golde, Todd E; Borchelt, David R; Giasson, Benoit I; Moehle, Mark S

A novel pThr217 tau monoclonal antibody reveals neuropathological heterogeneity in tauopathies

新型pThr217 tau单克隆抗体揭示tau蛋白病中的神经病理学异质性

Paterno, Giavanna; Bell, Brach M; Gorion, Kimberly-Marie M; Quintin, Stephan; Prokop, Stefan; Giasson, Benoit I

Uncovering α-synuclein and tau burden in Alzheimer's and Lewy body diseases

揭示阿尔茨海默病和路易体病中的α-突触核蛋白和tau蛋白负荷

Quintin, Stephan; Paterno, Giavanna; Lloyd, Grace M; Prokop, Stefan; Giasson, Benoit I

Correction: Collusion of α-Synuclein and Aβ aggravating co-morbidities in a novel prion-type mouse model

更正:α-突触核蛋白和Aβ的协同作用加剧了新型朊病毒型小鼠模型中的合并症

Lloyd, Grace M; Dhillon, Jess-Karan S; Gorion, Kimberly-Marie M; Riffe, Cara; Fromholt, Susan E; Xia, Yuxing; Giasson, Benoit I; Borchelt, David R

A multiverse of α-synuclein: investigation of prion strain properties with carboxyl-terminal truncation specific antibodies in animal models

α-突触核蛋白的多元宇宙:利用羧基末端截短特异性抗体在动物模型中研究朊病毒株的特性

Lloyd, Grace M; Quintin, Stephan; Sorrentino, Zachary A; Gorion, Kimberly-Marie M; Bell, Brach M; Long, Brooke; Paterno, Giavanna; Giasson, Benoit I

Neuronal tissue collection from intra-cranial instruments used in deep brain stimulation surgery for Parkinson's disease with implications for study of alpha-synuclein

从用于治疗帕金森病的深部脑刺激手术的颅内器械中收集神经组织,对 α-突触核蛋白的研究具有重要意义

Zachary A Sorrentino, Joshua Riklan, Grace M Lloyd, Brandon P Lucke-Wold, David Mampre, Stephan Quintin, Rasheedat Zakare-Fagbamila, Megan Still, Vyshak Chandra, Kelly D Foote, Benoit I Giasson, Justin D Hilliard

Novel Monoclonal Antibody Specific toward Amyloid-β Binds to a Unique Epitope within the N-Terminal Region

一种新型的针对β-淀粉样蛋白的单克隆抗体,可结合N端区域内的独特表位。

Paterno, Giavanna; Moore, Brenda D; Bell, Brach M; Gorion, Kimberly-Marie M; Ran, Yong; Prokop, Stefan; Golde, Todd E; Giasson, Benoit I

Human tauopathy strains defined by phosphorylation in R1-R2 repeat domains of tau

人类 tau 蛋白病菌株通过 tau 的 R1-R2 重复域磷酸化定义

Ethan D Smith, Quan Vo, Benoit I Giasson, David R Borchelt, Stefan Prokop, Paramita Chakrabarty

Carboxyl truncation of α-synuclein occurs early and is influenced by human APOE genotype in transgenic mouse models of α-synuclein pathogenesis

α-突触核蛋白的羧基截断发生较早,并且在α-突触核蛋白致病性的转基因小鼠模型中受人类APOE基因型的影响。

Lloyd, Grace M; Long, Brooke; Quintin, Stephan; Sorrentino, Zachary A; Gorion, Kimberly-Marie M; Bell, Brach M; Carrillo, Denise; Sullivan, Patrick; Borchelt, David; Giasson, Benoit I