日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Role of G Protein-Coupled Receptors and Receptor Kinases in Pancreatic β-Cell Function and Diabetes

G蛋白偶联受体和受体激酶在胰岛β细胞功能和糖尿病中的作用

Varney, Matthew J; Benovic, Jeffrey L

Introducing a machine learning algorithm for delirium prediction-the Supporting SURgery with GEriatric Co-Management and AI project (SURGE-Ahead)

引入用于谵妄预测的机器学习算法——老年医学协同管理和人工智能支持手术项目(SURGE-Ahead)

Benovic, Samuel; Ajlani, Anna H; Leinert, Christoph; Fotteler, Marina; Wolf, Dennis; Steger, Florian; Kestler, Hans; Dallmeier, Dhayana; Denkinger, Michael; Eschweiler, Gerhard W; Thomas, Christine; Kocar, Thomas D

Diverse pathways in GPCR-mediated activation of Ca(2+) mobilization in HEK293 cells

HEK293细胞中GPCR介导的Ca(2+)动员激活的多种途径

De Pascali, Francesco; Inoue, Asuka; Benovic, Jeffrey L

How carvedilol does not activate β(2)-adrenoceptors

卡维地洛如何不激活β(2)-肾上腺素受体

Lefkowitz, Robert J; Rockman, Howard A; Shim, Paul J; Liu, Samuel; Ahn, Seungkirl; Pani, Biswaranjan; Rajagopal, Sudarshan; Shenoy, Sudha K; Bouvier, Michel; Benovic, Jeffrey L; Liggett, Stephen B; Ruffolo, Robert R; Bristow, Michael R; Packer, Milton

IGF1R Inhibition Enhances the Therapeutic Effects of Gq/11 Inhibition in Metastatic Uveal Melanoma Progression

IGF1R 抑制可增强 Gq/11 抑制对转移性葡萄膜黑色素瘤进展的治疗效果

Dominic Lapadula, Bao Lam, Mizue Terai, Takahito Sugase, Ryota Tanaka, Eduardo Farias, Rama Kadamb, Melisa Lopez-Anton, Christian C Heine, Bhavik Modasia, Julio A Aguirre-Ghiso, Andrew E Aplin, Takami Sato, Jeffrey L Benovic

Kinome profiling identifies MARK3 and STK10 as potential therapeutic targets in uveal melanoma

激酶组分析确定 MARK3 和 STK10 是葡萄膜黑色素瘤的潜在治疗靶点

Usman Baqai, Alison M Kurimchak, Isabella V Trachtenberg, Timothy J Purwin, Jelan I Haj, Anna Han, Kristine Luo, Nikole Fandino Pachon, Angela Jeon, Vivian Chua, Michael A Davies, J Silvio Gutkind, Jeffrey L Benovic, James S Duncan, Andrew E Aplin

Pepducin ICL1-9-Mediated β2-Adrenergic Receptor-Dependent Cardiomyocyte Contractility Occurs in a Gi Protein/ROCK/PKD-Sensitive Manner

Pepducin ICL1-9 介导的 β2-肾上腺素受体依赖性心肌细胞收缩以 Gi 蛋白/ROCK/PKD 敏感的方式发生

Ama Dedo Okyere, Jianliang Song, Viren Patwa, Rhonda L Carter, Nitya Enjamuri, Anna Maria Lucchese, Jessica Ibetti, Claudio de Lucia, Sarah M Schumacher, Walter J Koch, Joseph Y Cheung, Jeffrey L Benovic, Douglas G Tilley

β2 -Adrenoceptor agonist profiling reveals biased signalling phenotypes for the β2 -adrenoceptor with possible implications for the treatment of asthma

β2-肾上腺素能受体激动剂分析揭示了 β2-肾上腺素能受体的偏向信号传导表型,可能对哮喘的治疗有影响

Francesco De Pascali, Michael Ippolito, Emily Wolfe, Konstantin E Komolov, Nathan Hopfinger, Douglas Lemenze, Nicholas Kim, Roger S Armen, Steven S An, Charles P Scott, Jeffrey L Benovic

PD 102807 Induces M3 mAChR-Dependent GRK-/Arrestin-Biased Signaling in Airway Smooth Muscle Cells

PD 102807 诱导气道平滑肌细胞中 M3 mAChR 依赖的 GRK/Arrestin 偏向性信号传导

Tompkins, Eric; Mimic, Bogdana; Cuevas-Mora, Karina; Schorsch, Hannah; Shah, Sushrut D; Deshpande, Deepak A; Benovic, Jeffrey L; Penn, Raymond B; Pera, Tonio

G protein-coupled receptor kinase 6 (GRK6) regulates insulin processing and secretion via effects on proinsulin conversion to insulin

蛋白偶联受体激酶 6 (GRK6) 通过影响胰岛素原转化为胰岛素来调节胰岛素的加工和分泌

Matthew J Varney, Wouter Steyaert, Paul J Coucke, Joris R Delanghe, David E Uehling, Babu Joseph, Richard Marcellus, Rima Al-Awar, Jeffrey L Benovic