Proteomic and metabolic profiling reveals APOE4-dependent shifts in whole brain, neuronal, and astrocytic mitochondrial function and glycolysis.
蛋白质组学和代谢组学分析揭示了 APOE4 依赖性的全脑、神经元和星形胶质细胞线粒体功能和糖酵解的变化
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doi:10.1101/2025.06.15.659811
Lysaker Colton R, Johnson Chelsea N, Csikos Vivien, Franczak Edziu, Benson Maggie, Gilmore Caleb A, Birky Cole J, Davis Xin, McCoin Colin S, Smith Keith P, Puchalska Patrycja, Crawford Peter, Slawson Chad, Thyfault John P, Geiger Paige C, Morris Jill K, Wilkins Heather M