Single-cell spatial transcriptomics reveals distinct patterns of dysregulation in non-neuronal and neuronal cells induced by the Trem2(R47H) Alzheimer's risk gene mutation
单细胞空间转录组学揭示了由Trem2(R47H)阿尔茨海默病风险基因突变引起的非神经元细胞和神经元细胞中不同的失调模式。
期刊:Molecular Psychiatry
影响因子:10.1
doi:10.1038/s41380-024-02651-0
Johnston, Kevin G; Berackey, Bereket T; Tran, Kristine M; Gelber, Alon; Yu, Zhaoxia; MacGregor, Grant R; Mukamel, Eran A; Tan, Zhiqun; Green, Kim N; Xu, Xiangmin