日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Single-cell spatial transcriptomics reveals distinct patterns of dysregulation in non-neuronal and neuronal cells induced by the Trem2(R47H) Alzheimer's risk gene mutation

单细胞空间转录组学揭示了由Trem2(R47H)阿尔茨海默病风险基因突变引起的非神经元细胞和神经元细胞中不同的失调模式。

Johnston, Kevin G; Berackey, Bereket T; Tran, Kristine M; Gelber, Alon; Yu, Zhaoxia; MacGregor, Grant R; Mukamel, Eran A; Tan, Zhiqun; Green, Kim N; Xu, Xiangmin

An AAV capsid proposed as microglia-targeting directs genetic expression in forebrain excitatory neurons.

一种被提出作为小胶质细胞靶向载体的 AAV 衣壳,可指导前脑兴奋性神经元中的基因表达

Cao Wenhao, Tan Zhiqun, Berackey Bereket T, Nguyen Jason K, Brown Sara R, Du Shiyang, Lin Bin, Ye Qiao, Seiler Magdalene, Holmes Todd C, Xu Xiangmin

Single cell spatial transcriptomics reveals distinct patterns of dysregulation in non-neuronal and neuronal cells induced by the Trem2(R47H) Alzheimer's risk gene mutation

单细胞空间转录组学揭示了由Trem2(R47H)阿尔茨海默病风险基因突变引起的非神经元细胞和神经元细胞中不同的失调模式

Johnston, Kevin; Berackey, Bereket B; Tran, Kristine Minh; Gelber, Alon; Yu, Zhaoxia; MacGregor, Grant; Mukamel, Eran A; Tan, Zhiqun; Green, Kim; Xu, Xiangmin