日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Structure-Based Discovery of Potent and Selective Small-Molecule α5β1 Integrin Inhibitors for Asthma Therapy

基于结构的高效选择性小分子α5β1整合素抑制剂的发现及其在哮喘治疗中的应用

期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.5c10068
Beresis, Richard; Sundaram, Aparna; Jo, Hyunil; Adler, Marc; Wang, Zheng; McIntosh, Joel; Yeon, Seul Ki; Huang, Qiuya; Ngo, Grace; Sheppard, Dean; DeGrado, William F
哮喘
发表日期：2025
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Exploration of a Class of Aryl Imidazolyl Ureas As Potent Acid Ceramidase Inhibitors for the Treatment of Fibrotic Diseases.

探索一类芳基咪唑基脲作为强效酸性神经酰胺酶抑制剂在治疗纤维化疾病中的应用

期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.5c03734
Beresis Richard, Prathigudupu Vijaya, Cable Carson, Yu Amy, Adler Marc, Ramamoorthi Roopa, Yeon Seul Ki, Gordan John D, Sharma Sachin, DeGrado William F, Zaro Balyn, Chen Jennifer Y, Jo Hyunil
神经科学
发表日期：2025
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Resolving fibrosis by stimulating HSC-dependent extracellular matrix degradation

通过刺激 HSC 依赖性细胞外基质降解来消除纤维化

期刊:Science Translational Medicine
影响因子:
doi:10.1126/scitranslmed.ads9470
Sharma, Sachin; Prathigudupu, Vijaya; Cable, Carson; Serrano, Lia R; Nerella, Srilaxmi; Chen, Alina; Hassan, Ghmkin; Lakins, Johnathon; Valenzuela, Carlos Lizama; Tsukui, Tatsuya; Ramamoorthi, Roopa; Kim, Jae-Jun; Willenbring, Holger; Mattis, Aras N; Volk, Regan F; Zaro, Balyn W; Coon, Joshua J; Beresis, Richard; DeGrado, William F; Weaver, Valerie M; Christenson, Stephanie A; Jo, Hyunil; Chen, Jennifer Y
细胞生物学
发表日期：2025
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Oligomeric State and Drug Binding of the SARS-CoV-2 Envelope Protein Are Sensitive to the Ectodomain

SARS-CoV-2包膜蛋白的寡聚状态和药物结合对胞外结构域敏感。

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.4c07686
Somberg, Noah H; Sučec, Iva; Medeiros-Silva, João; Jo, Hyunil; Beresis, Richard; Syed, Abdullah M; Doudna, Jennifer A; Hong, Mei
SARS-CoV-2
发表日期：2024
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Dual antagonists of α5β1/αvβ1 integrin for airway hyperresponsiveness

用于治疗气道高反应性的α5β1/αvβ1整合素双重拮抗剂

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2020.127578
Sundaram, Aparna; Chen, Chun; Isik Reed, Nilgun; Liu, Sean; Ki Yeon, Seul; McIntosh, Joel; Tang, You-Zhi; Yang, Hyunjun; Adler, Marc; Beresis, Richard; Seiple, Ian B; Sheppard, Dean; DeGrado, William F; Jo, Hyunil
发表日期：2020
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