The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors
小分子GMX1778是NAD+生物合成的强效抑制剂:增强烟酸磷酸核糖转移酶1缺陷型肿瘤治疗的策略
期刊:Molecular and Cellular Biology
影响因子:2.7
doi:10.1128/MCB.00112-09
Watson, Mark; Roulston, Anne; Bélec, Laurent; Billot, Xavier; Marcellus, Richard; Bédard, Dominique; Bernier, Cynthia; Branchaud, Stéphane; Chan, Helen; Dairi, Kenza; Gilbert, Karine; Goulet, Daniel; Gratton, Michel-Olivier; Isakau, Henady; Jang, Anne; Khadir, Abdelkrim; Koch, Elizabeth; Lavoie, Manon; Lawless, Michael; Nguyen, Mai; Paquette, Denis; Turcotte, Emilie; Berger, Alvin; Mitchell, Matthew; Shore, Gordon C; Beauparlant, Pierre