日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genetic and epigenetic characterization of sarcoma stem cells across subtypes identifies EZH2 as a therapeutic target

对不同亚型肉瘤干细胞的遗传和表观遗传特征分析表明,EZH2 是一个潜在的治疗靶点。

O'Donnell, Edmond 3rd; Muñoz, Maria; Davis, Ryan; Bergonio, Jessica; Randall, R Lor; Tepper, Clifford; Carr-Ascher, Janai

Genetic Screen in a Preclinical Model of Sarcoma Development Defines Drivers and Therapeutic Vulnerabilities

在肉瘤发展的临床前模型中进行基因筛选,确定驱动因素和治疗弱点

Jack Freeland # ,Maria Muñoz # ,Edmond O'Donnell 3rd ,Justin Langerman ,Morgan Darrow ,Jessica Bergonio ,Julissa Suarez-Navarro ,Steven Thorpe ,Robert Canter ,Robert Lor Randall ,Kathrin Plath ,Kermit L Carraway 3rd ,Owen N Witte ,Thomas G Graeber ,Janai R Carr-Ascher