Discovery of AZD4144, a Selective and Potent NLRP3 Inhibitor for the Treatment of Inflammatory Diseases.
发现 AZD4144，一种选择性强效的 NLRP3 抑制剂，可用于治疗炎症性疾病
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c00781
Johansson Anders, Sugama Hiroshi, Larsson Niklas, Winiwarter Susanne, Yoshida Kosuke, Gradén Henrik, Bergonzini Giulia, Matsumura Takehiko, Miyazaki Shiki, Fuchigami Ryuichi, Eda Masahiro, Takamatsu Hisayuki, Iguchi Kaori, Hongu Mitsuya, Matsudaira Tetsuji, Hovdal Daniel, Fredenwall Marlene, Fahlander Ulf, Luchniak Anna, Brengdahl Johan, Jung Bomi, Rhedin Magdalena, Sardana Juhi, Idei Akiko, Kato Yosuke, Kimura Junpei, Viklund Jenny, Brandt Peter, Sjögren Anna-Karin, Hibino Yui, Woollard Kevin, Yoneda Hikaru
