日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Is a Malleable Active Site Loop the Key to High Substrate Promiscuity? Hybrid, Biocatalytic Route to Structurally Diverse Taxoid Side Chains with Remarkable Dual Stereocontrol

可塑性活性位点环是实现高底物混杂性的关键吗？一种具有卓越双重立体控制的结构多样化紫杉烷侧链的混合生物催化途径

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202510889
Kudalkar, Gaurav P; Leidner, Florian; Kumar, Nivesh; Hass, Jared L; Madzelan, Peter; Powell, Douglas R; Day, Victor W; Magueres, Pierre Le; Ferrara, Joseph D; Daniels, Lee M; Yamano, Akihito; Ito, Sho; Niu, Wei; Grubmüller, Helmut; Wilson, Mark A; Berkowitz, David B
发表日期：2025
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α-Hydrazino Acids Inhibit Pyridoxal Phosphate-Dependent Decarboxylases via "Catalytically Correct" Ketoenamine Tautomers: A Special Motif for Chemical Biology and Drug Discovery?

α-肼酸通过“催化正确的”酮烯胺互变异构体抑制磷酸吡哆醛依赖性脱羧酶：化学生物学和药物发现的特殊基序？

期刊:ACS Catalysis
影响因子:13.1
doi:10.1021/acscatal.5c00326
Baine, Jonathan M; Duhoo, Yoan; Doukov, Tzanko; Desfosses, Ambroise; Bisello, Giovanni; Beio, Matthew L; Bauer, Olivia; Perduca, Massimiliano; Bacia-Verloop, Maria; Bertoldi, Mariarita; Phillips, Robert S; Gutsche, Irina; Berkowitz, David B
发表日期：2025
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Identification of Potential Prophylactic Medical Countermeasures Against Acute Radiation Syndrome (ARS).

识别针对急性放射综合征（ARS）的潜在预防性医疗对策

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26094055
Liermann-Wooldrik Kia T, Chatterjee Arpita, Kosmacek Elizabeth A, Myers Molly S, Adebisi Oluwaseun, Monga-Wells Louise, Mei Liu, Takacs Michelle P, Dussault Patrick H, Draney Daniel R, Powers Robert, Checco James W, Guda Chittibabu, Helikar Tomáš, Berkowitz David B, Bayles Kenneth W, Epstein Alan H, Cary Lynnette, Murry Daryl J, Oberley-Deegan Rebecca E
发表日期：2025
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Exploiting Archaeal/Thermostable Enzymes in Synthetic Chemistry: Back to the Future?

利用古细菌/耐热酶进行合成化学：回到未来？

期刊:ChemCatChem
影响因子:3.9
doi:10.1002/cctc.202400835
Kudalkar, Gaurav P; Tiwari, Virendra K; Berkowitz, David B
微生物学
发表日期：2024
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Information-Rich, Dual-Function (13)C/(2)H-Isotopic Crosstalk NMR Assay for Human Serine Racemase (hSR) Provides a PLP-Enzyme "Partitioning Fingerprint" and Reveals Disparate Chemotypes for hSR Inhibition

信息丰富的双功能 (13)C/(2)H 同位素串扰 NMR 分析法用于人丝氨酸消旋酶 (hSR)，提供 PLP 酶“分配指纹图谱”，并揭示 hSR 抑制的不同化学类型

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.2c12774
Ramos de Dios, Stephany M; Hass, Jared L; Graham, Danielle L; Kumar, Nivesh; Antony, Aina E; Morton, Martha D; Berkowitz, David B
Human
发表日期：2023
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A Review of Radiation-Induced Alterations of Multi-Omic Profiles, Radiation Injury Biomarkers, and Countermeasures

辐射诱导的多组学特征改变、辐射损伤生物标志物及应对措施综述

期刊:Radiation Research
影响因子:2.7
doi:10.1667/RADE-21-00187.1
Shakyawar, Sushil K; Mishra, Nitish K; Vellichirammal, Neetha N; Cary, Lynnette; Helikar, Tomáš; Powers, Robert; Oberley-Deegan, Rebecca E; Berkowitz, David B; Bayles, Kenneth W; Singh, Vijay K; Guda, Chittibabu
辐射损伤
毒理研究
发表日期：2023
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Changes in an Enzyme Ensemble During Catalysis Observed by High Resolution XFEL Crystallography

利用高分辨率XFEL晶体学观察催化过程中酶复合物的变化

期刊:
影响因子:
doi:10.1101/2023.08.15.553460
Smith, Nathan; Dasgupta, Medhanjali; Wych, David C; Dolamore, Cole; Sierra, Raymond G; Lisova, Stella; Marchany-Rivera, Darya; Cohen, Aina E; Boutet, Sébastien; Hunter, Mark S; Kupitz, Christopher; Poitevin, Frédéric; Moss, Frank R 3rd; Brewster, Aaron S; Sauter, Nicholas K; Young, Iris D; Wolff, Alexander M; Tiwari, Virendra K; Kumar, Nivesh; Berkowitz, David B; Hadt, Ryan G; Thompson, Michael C; Follmer, Alec H; Wall, Michael E; Wilson, Mark A
发表日期：2023
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Biomacromolecule-Assisted Screening for Reaction Discovery and Catalyst Optimization

生物大分子辅助筛选用于反应发现和催化剂优化

期刊:Chemical Reviews
影响因子:55.8
doi:10.1021/acs.chemrev.2c00213
Ramos De Dios, Stephany M; Tiwari, Virendra K; McCune, Christopher D; Dhokale, Ranjeet A; Berkowitz, David B
发表日期：2022
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A Hammett Study of Clostridium acetobutylicum Alcohol Dehydrogenase (CaADH): An Enzyme with Remarkable Substrate Promiscuity and Utility for Organic Synthesis

哈米特对丙酮丁醇梭菌醇脱氢酶（CaADH）的研究：一种具有显著底物混杂性和在有机合成中应用价值的酶

期刊:Synlett
影响因子:1.4
doi:10.1055/s-0039-1691576
Kudalkar, Gaurav P; Tiwari, Virendra K; Lee, Joshua D; Berkowitz, David B
发表日期：2020
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Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis

混合注入式XFEL晶体学揭示酶催化过程中门控构象动力学

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1901864116
Dasgupta, Medhanjali; Budday, Dominik; de Oliveira, Saulo H P; Madzelan, Peter; Marchany-Rivera, Darya; Seravalli, Javier; Hayes, Brandon; Sierra, Raymond G; Boutet, Sébastien; Hunter, Mark S; Alonso-Mori, Roberto; Batyuk, Alexander; Wierman, Jennifer; Lyubimov, Artem; Brewster, Aaron S; Sauter, Nicholas K; Applegate, Gregory A; Tiwari, Virendra K; Berkowitz, David B; Thompson, Michael C; Cohen, Aina E; Fraser, James S; Wall, Michael E; van den Bedem, Henry; Wilson, Mark A
发表日期：2019
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