Simultaneous assessment of Asp isomerization and Asn deamidation in recombinant antibodies by LC-MS following incubation at elevated temperatures
高温孵育后通过 LC-MS 同时评估重组抗体中的 Asp 异构化和 Asn 脱酰胺作用
期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0030295
Katharina Diepold, Katrin Bomans, Michael Wiedmann, Boris Zimmermann, Andreas Petzold, Tilman Schlothauer, Robert Mueller, Bernd Moritz, Jan Olaf Stracke, Michael Mølhøj, Dietmar Reusch, Patrick Bulau