日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

RNA-based co-transfer of human CD8αβ with WT1-specific TCRαβ redirects tumor recognition by CD4 and γδ T-cells towards MHC class I-restricted WT1 epitopes and boosts CD8 T-cell responses with or without CD3 mRNA

基于RNA的人CD8αβ与WT1特异性TCRαβ共转移，可将CD4和γδ T细胞对肿瘤的识别重定向至MHC I类限制性WT1表位，并增强CD8 T细胞应答，无论是否存在CD3 mRNA。

期刊:Experimental Hematology & Oncology
影响因子:13.5
doi:10.1186/s40164-026-00764-6
Campillo-Davo, Diana; Flumens, Donovan; Berneman, Zwi N; Fujiki, Fumihiro; Roex, Gils; Versteven, Maarten; Van Acker, Heleen H; Van Tendeloo, Viggo F I; Sugiyama, Haruo; Anguille, Sébastien; Lion, Eva
肿瘤
T细胞
肿瘤免疫
CD8
CD3
T细胞
WT1
细胞生物学
CD4
免疫/内分泌
发表日期：2026
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Resilience of human tolerogenic dendritic cells to physiological oxygen supports clinical application: functional stability amidst glycolytic and differentiation shifts

人类耐受性树突状细胞对生理氧的适应能力支持其临床应用：在糖酵解和分化转变过程中保持功能稳定性

期刊:Experimental Hematology & Oncology
影响因子:13.5
doi:10.1186/s40164-025-00731-7
Peter, Antonia; Traitteur, Tamara; Calitz, Sara; Vermeulen, Morgane; Van Delen, Mats; Dams, Amber; Peeters, Stefanie; Faghel, Carole; De Reu, Hans; Marei, Waleed F A; Berneman, Zwi N; Cools, Nathalie
树突状细胞
细胞生物学
树突状细胞
免疫/内分泌
发表日期：2026
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WT1-mRNA dendritic cell vaccination of patients with glioblastoma multiforme, malignant pleural mesothelioma, metastatic breast cancer, and other solid tumors: type 1 T-lymphocyte responses are associated with clinical outcome

WT1-mRNA树突状细胞疫苗接种治疗多形性胶质母细胞瘤、恶性胸膜间皮瘤、转移性乳腺癌和其他实体瘤患者：1型T淋巴细胞反应与临床疗效相关

期刊:Journal of Hematology & Oncology
影响因子:40.4
doi:10.1186/s13045-025-01661-x
Berneman, Zwi N; De Laere, Maxime; Germonpré, Paul; Huizing, Manon T; Willemen, Yannick; Lion, Eva; De Reu, Hans; Van den Bossche, Jolien; Van den Brande, Jan; Specenier, Pol; Altintas, Sevilay; van Dam, Peter A; Cools, Nathalie; Nijs, Griet; Stein, Barbara; Caluwaerts, Kim; Snoeckx, Annemiek; Op de Beeck, Bart; Saevels, Kirsten; Rutsaert, Lynn; Vandenbosch, Irma; Oner, Gizem; Lammens, Martin; Van Damme, Pierre; Llewellyn-Lacey, Sian; Price, David A; Oka, Yoshihiro; Oji, Yusuke; Sugiyama, Haruo; Couttenye, Marie M; Van de Velde, Ann L; Van Tendeloo, Viggo F; Peeters, Marc; Anguille, Sébastien; Smits, Evelien L J M
肿瘤
肿瘤免疫
树突状细胞
乳腺癌
WT1
细胞生物学
树突状细胞
免疫/内分泌
发表日期：2025
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Correction: WT1-mRNA dendritic cell vaccination of patients with glioblastoma multiforme, malignant pleural mesothelioma, metastatic breast cancer, and other solid tumors: type 1 T-lymphocyte responses are associated with clinical outcome

更正：WT1-mRNA树突状细胞疫苗接种治疗多形性胶质母细胞瘤、恶性胸膜间皮瘤、转移性乳腺癌和其他实体瘤患者：1型T淋巴细胞反应与临床结果相关

期刊:Journal of Hematology & Oncology
影响因子:40.4
doi:10.1186/s13045-025-01683-5
Berneman, Zwi N; De Laere, Maxime; Germonpré, Paul; Huizing, Manon T; Willemen, Yannick; Lion, Eva; De Reu, Hans; Van den Bossche, Jolien; Van den Brande, Jan; Specenier, Pol; Altintas, Sevilay; van Dam, Peter A; Cools, Nathalie; Nijs, Griet; Stein, Barbara; Caluwaerts, Kim; Snoeckx, Annemiek; de Beeck, Bart Op; Saevels, Kirsten; Rutsaert, Lynn; Vandenbosch, Irma; Oner, Gizem; Lammens, Martin; Van Damme, Pierre; Llewellyn-Lacey, Sian; Price, David A; Oka, Yoshihiro; Oji, Yusuke; Sugiyama, Haruo; Couttenye, Marie M; Van de Velde, Ann L; Van Tendeloo, Viggo F; Peeters, Marc; Anguille, Sébastien; Smits, Evelien L J M
肿瘤
肿瘤免疫
树突状细胞
乳腺癌
WT1
细胞生物学
树突状细胞
免疫/内分泌
发表日期：2025
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Physiological Oxygen Levels in the Microenvironment Program Ex Vivo-Generated Conventional Dendritic Cells Toward a Tolerogenic Phenotype

微环境生理氧水平程序诱导体外生成的常规树突状细胞向耐受表型转变

期刊:Cells
影响因子:5.1
doi:10.3390/cells14100736.
Antonia Peter ,Morgane Vermeulen ,Mats Van Delen ,Amber Dams ,Stefanie Peeters ,Hans De Reu ,Waleed F A Marei ,Zwi N Berneman ,Nathalie Cools
树突状细胞
细胞生物学
树突状细胞
免疫/内分泌
发表日期：2025
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Tumor Microenvironment Modulation by Tumor-Associated Macrophages: Implications for Neoadjuvant Chemotherapy Response in Breast Cancer

肿瘤相关巨噬细胞对肿瘤微环境的调控：对乳腺癌新辅助化疗反应的影响

期刊:Breast Cancer-Targets and Therapy
影响因子:3.4
doi:10.2147/BCTT.S493085
Oner, Gizem; Praet, Marleen Marguerite; Stoop, Hans; Devi, Gayathri R; Canturk, Nuh Zafer; Altintas, Sevilay; Van Berckelaer, Christophe; Berneman, Zwi; Tjalma, Wiebren; Koljenovic, Senada; van Dam, Peter A
巨噬细胞
肿瘤
肿瘤免疫
巨噬细胞
信号转导
乳腺癌
细胞生物学
肿瘤微环境
免疫/内分泌
发表日期：2025
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Analysis of Wilms' tumor protein 1 specific TCR repertoire in AML patients uncovers higher diversity in patients in remission than in relapsed

对急性髓系白血病（AML）患者中威尔姆斯肿瘤蛋白1特异性T细胞受体（TCR）库的分析发现，缓解期患者的TCR库多样性高于复发期患者。

期刊:Annals of Hematology
影响因子:2.4
doi:10.1007/s00277-024-05919-1
Gielis, Sofie; Flumens, Donovan; van der Heijden, Sanne; Versteven, Maarten; De Reu, Hans; Bartholomeus, Esther; Schippers, Jolien; Campillo-Davo, Diana; Berneman, Zwi N; Anguille, Sébastien; Smits, Evelien; Ogunjimi, Benson; Lion, Eva; Laukens, Kris; Meysman, Pieter
肿瘤
T细胞
肿瘤免疫
信号转导
白血病
T细胞
细胞生物学
免疫/内分泌
发表日期：2025
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Integration of the PD-L1 inhibitor atezolizumab and WT1/DC vaccination into standard-of-care first-line treatment for patients with epithelioid malignant pleural mesothelioma-Protocol of the Immuno-MESODEC study

将PD-L1抑制剂阿特珠单抗和WT1/DC疫苗整合到上皮样恶性胸膜间皮瘤患者的一线标准治疗方案中——Immuno-MESODEC研究方案

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0307204
Van den Bossche, Jolien; De Laere, Maxime; Deschepper, Koen; Germonpré, Paul; Valcke, Yvan; Lamont, Jan; Stein, Barbara; Van Camp, Kirsten; Germonpré, Charlotte; Nijs, Griet; Roelant, Ella; Anguille, Sébastien; Lion, Eva; Berneman, Zwi
PD-L1
WT1
发表日期：2024
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Adjuvant Wilms' tumour 1-specific dendritic cell immunotherapy complementing conventional therapy for paediatric patients with high-grade glioma and diffuse intrinsic pontine glioma: protocol of a monocentric phase I/II clinical trial in Belgium

辅助性 Wilms 肿瘤 1 特异性树突状细胞免疫疗法可补充常规疗法，用于治疗儿童高级别胶质瘤和弥漫性内生性脑桥胶质瘤：一项在比利时开展的单中心 I/II 期临床试验方案

期刊:BMJ Open
影响因子:2.3
doi:10.1136/bmjopen-2023-077613
Van Genechten, Toon; De Laere, Maxime; Van den Bossche, Jolien; Stein, Barbara; De Rycke, Kim; Deschepper, Caroline; Hazes, Katja; Peeters, Renke; Couttenye, Marie-Madeleine; Van De Walle, Katrien; Roelant, Ella; Maes, Sabine; Vanden Bossche, Stephanie; Dekeyzer, Sven; Huizing, Manon; Caluwaert, Kim; Nijs, Griet; Cools, Nathalie; Verlooy, Joris; Norga, Koen; Verhulst, Stijn; Anguille, Sebastien; Berneman, Zwi; Lion, Eva
肿瘤
肿瘤免疫
细胞生物学
树突状细胞
神经科学
胶质瘤
树突状细胞
免疫/内分泌
发表日期：2024
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The immune microenvironment characterisation and dynamics in hormone receptor-positive breast cancer before and after neoadjuvant endocrine therapy

新辅助内分泌治疗前后激素受体阳性乳腺癌免疫微环境的特征和动态变化

期刊:Cancer Medicine
影响因子:3.1
doi:10.1002/cam4.6425
Oner, Gizem; Broeckx, Glenn; Van Berckelaer, Christophe; Zwaenepoel, Karen; Altintas, Sevilay; Canturk, Zafer; Tjalma, Wiebren; Berneman, Zwi; Peeters, Marc; Pauwels, Patrick; van Dam, Peter A
肿瘤
肿瘤免疫
信号转导
乳腺癌
免疫/内分泌
发表日期：2023
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