日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Population pharmacokinetics of lumefantrine in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum malaria in Western Kenya

肯尼亚西部地区妊娠期和非妊娠期单纯性恶性疟疾患者服用卢美芬汀的群体药代动力学研究

Juma, Elizabeth; Ding, Junjie; Ongas, Martin; Koskei, Nelly; Onyango, Kevin; Oloo, Florence; Aman, Rashid; Kokwaro, Gilbert; Tarning, Joel; Ogutu, Bernhards

National research ecosystems: protecting populations and building health security worldwide

国家科研生态系统:保护民众,构建全球健康安全

Higgs, Elizabeth S; Altaf, Arshad; Lurie, Nicole; Fotouhi, Akbar; Kilmarx, Peter H; Nyirenda, Tom; Ogutu, Bernhards; Rani, Manju; Doumbia, Seydou; Sprumont, Dominique; van Delden, Johannes J M; Sorenson, Robert A; Moorthy, Vasee; Farrar, Jeremy

Safety, tolerability, and immunogenicity of a DNA-based vaccine (INO-4700) against Middle East respiratory syndrome coronavirus: phase 2a study in healthy volunteers

DNA疫苗(INO-4700)对抗中东呼吸综合征冠状病毒的安全性、耐受性和免疫原性:健康志愿者中的2a期研究

Agnes, Joseph T; Marcus, Sarah A; Al-Ghraibeh, Sahem S; Al-Sweedan, Suleimman Ahmad; Kosgei, Josphat; Ogutu, Bernhards; Yang, ShuPing; Walker, Kathleen A; Orizu, Bonaventure; Broderick, Kate E; Boyer, Jean; Ramos, Stephanie; Morrow, Matthew P; Kraynyak, Kimberly; Sylvester, Albert J; Gillespie, Elisabeth; Liebowitz, David; Humeau, Laurent M

Pharmacokinetics, safety and efficacy of an optimized dose of artemether-lumefantrine in the treatment of acute uncomplicated Plasmodium falciparum malaria in neonates and infants of less than 5 kg body weight: a multicentre, open-label, single-arm phase 2/3 study (CALINA)

优化剂量蒿甲醚-苯芴醇治疗体重小于 5 公斤的新生儿和婴儿急性单纯性恶性疟疾的药代动力学、安全性和有效性:一项多中心、开放标签、单臂 2/3 期研究 (CALINA)

Wounounou, Gildas; Tiono, Alfred B; Ogutu, Bernhards; Manyando, Christine; Sagara, Issaka; Schneitter, Stefan; Bassat, Quique; Gaaloul, Myriam El; Marrast, Anne Claire; Demin, Ivan; Winnips, Cornelis; Risterucci, Celine; Hugot, Sophie; Hofstetter, Georg; Qian, Zhiyan; Su, Guoqin; Zhang, Jie; Renner, Katalin Csermak; Cousin, Marc; Venishetty, Vinay Kumar; Sayyed, Sarfaraz; Gandhi, Preetam; Kabore, Berenger

Consistency and reproducibility of independent feedings using blood from two consecutive days at varying Plasmodium falciparum gametocyte densities based on both direct membrane feeding assay and direct skin feeding assay

基于直接膜喂养试验和直接皮肤喂养试验,利用连续两天采集的血液样本,在不同恶性疟原虫配子体密度下进行独立喂养试验,评估其一致性和可重复性。

Akala, Hoseah Miima; Aponte, John J; Achola, Millicent Anyango; Juma, Dennis W; Opot, Benjamin H; Maisiba, Risper N; Okoth, Raphael O; Juma, Jackline A; Mwakio, Edwin W; Mwalo, Maurine A; Oullo, David O; Abuom, David; Garges, Eric C; Eyase, Fredrick L; Tina, Lucas Otieno; Copeland, Nathanial K; Roth, Amanda; Mutunga, James; Onyango, Irene; Johnson, Jaree; Ogutu, Bernhards R; Sifuna, Peter; Hutter, Jack; Mercer, Laina; Raine, Mike; Moore, Valerie; Ivinson, Karen; Wu, Yimin; Andagalu, Ben; Ockenhouse, Christian F

Advancing pharmacometrics in Africa-Transition from capacity development toward job creation

推进非洲的药物计量学发展——从能力建设转向创造就业机会

Pillai, Goonaseelan Colin; Mouksassi, Samer; Asiimwe, Innocent G; Rayner, Craig R; Kern, Steven; Sinxadi, Phumla; Denti, Paolo; Decloedt, Eric; Waitt, Catriona; Ogutu, Bernhards R; de Greef, Rik

Pharmacokinetics of Ganaplacide and Lumefantrine in Adults, Adolescents, and Children with Plasmodium falciparum Malaria Treated with Ganaplacide Plus Lumefantrine Solid Dispersion Formulation: Analysis of Data from a Multinational Phase 2 Study

一项多中心 II 期研究的数据分析:在接受加那普拉西德联合卢美芬汀固体分散制剂治疗的恶性疟原虫疟疾成人、青少年和儿童中,加那普拉西德和卢美芬汀的药代动力学研究

Sangana, Ramachandra; Ogutu, Bernhards; Yeka, Adoke; Kusemererwa, Sylvia; Tinto, Halidou; Toure, Andre Offianan; Kibuuka, Afizi; Lingani, Moussa; Lourenço, Carlos; Mombo-Ngoma, Ghyslain; Nduba, Videlis; Landry N'Guessan, Tiacoh; Nassa, Guétawendé Job Wilfried; Nyantaro, Mary; Tina, Lucas Otieno; Anvikar, Anup; Sinha, Abhinav; Kaguthi, Grace; Fofana, Bakary; Grobusch, Martin Peter; Gaaloul, Myriam El; Marrast, Anne Claire; Pathan, Rashidkhan; Chikoto, Havana; Csermak, Katalin; Risterucci, Celine; Su, Guoqin; Winnips, Cornelis; Zhang, Jie; Zack, Julia

Protein target similarity is positive predictor of in vitro antipathogenic activity: a drug repurposing strategy for Plasmodium falciparum

蛋白质靶标相似性是体外抗病原体活性的正向预测因子:恶性疟原虫药物再利用策略

Mogire, Reagan M; Miruka, Silviane A; Juma, Dennis W; McNamara, Case W; Andagalu, Ben; Burrows, Jeremy N; Chenu, Elodie; Duffy, James; Ogutu, Bernhards R; Akala, Hoseah M

NANOPARTICLE-BASED formulation of dihydroartemisinin-lumefantrine duo-drugs: Preclinical Evaluation and enhanced antimalarial efficacy in a mouse model

基于纳米颗粒的二氢青蒿素-卢米凡特林双药配方:小鼠模型中的临床前评估和增强的抗疟功效

Pesila Akeyo Odera, Geoffrey Otieno, Joab Otieno Onyango, James Jorum Owuor, Florence Anyango Oloo, Martin Ongas, Jeremiah Gathirwa, Bernhards Ogutu

Defining the next generation of severe malaria treatment: a target product profile

定义下一代重症疟疾治疗方案:目标产品概况

Achan, Jane; Barry, Aïssata; Leroy, Didier; Kamara, George; Duparc, Stephan; Kaszubska, Wiweka; Gandhi, Preetam; Buffet, Bénédicte; Tshilab, Patrick; Ogutu, Bernhards; Taylor, Terrie; Krishna, Sanjeev; Richardson, Naomi; Ramachandruni, Hanu; Rietveld, Hans