日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Bioengineered iPSC-derived human macrophages with increased angiotensin-converting enzyme (ACE) expression suppress solid tumor growth.

生物工程改造的 iPSC 衍生的人类巨噬细胞，其血管紧张素转换酶 (ACE) 表达增加，可抑制实体瘤的生长。

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-026-02650-3
Shibata Tomohiro, Bhat Shabir, Cao DuoYao, Saito Suguru, Khan Noor, Bernstein Ellen A, Tokudome Takeshi, Okwan-Duodu Derick, Tourtellotte Warren G, Bernstein Kenneth E, Khan Zakir
Human
细胞生物学
巨噬细胞
ACE
巨噬细胞
发表日期：2026
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Peroxisome proliferator-activated receptor alpha is an essential factor in enhanced macrophage immune function induced by angiotensin-converting enzyme.

过氧化物酶体增殖激活受体α是血管紧张素转换酶诱导的巨噬细胞免疫功能增强的重要因素

期刊:Cellular & Molecular Immunology
影响因子:19.8
doi:10.1038/s41423-025-01257-y
Saito Suguru, Cao Duo-Yao, Bernstein Ellen A, Shibata Tomohiro, Jones Anthony E, Rios Amy, Hoshi Aoi O, Stotland Aleksandr B, Nishi Erika E, Van Eyk Jennifer E, Divakaruni Ajit, Khan Zakir, Bernstein Kenneth E
细胞生物学
巨噬细胞
发表日期：2025
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Classical and nonclassical effects of angiotensin-converting enzyme: How increased ACE enhances myeloid immune function

血管紧张素转换酶的经典和非经典效应：ACE 升高如何增强髓系免疫功能

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2024.107388
Bernstein, Kenneth E; Cao, DuoYao; Shibata, Tomohiro; Saito, Suguru; Bernstein, Ellen A; Nishi, Erika; Yamashita, Michifumi; Tourtellotte, Warren G; Zhao, Tuantuan V; Khan, Zakir
免疫/内分泌
发表日期：2024
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Myeloid cell ACE shapes cellular metabolism and function in PCSK-9 induced atherosclerosis.

髓系细胞ACE在PCSK-9诱导的动脉粥样硬化中影响细胞代谢和功能

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2023.1278383
Cao DuoYao, Saito Suguru, Xu LiMin, Fan Wei, Li Xiaomo, Ahmed Faizan, Jovanovic Predrag, Shibata Tomohiro, Che Mingtian, Bernstein Ellen A, Gianni Jorge, Divakaruni Ajit S, Okwan-Duodu Derick, Khan Zakir, Riera Celine E, Chen Fanfan, Bernstein Kenneth E
代谢
细胞生物学
动脉粥样硬化
发表日期：2023
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Novel roles of the renal angiotensin-converting enzyme

肾脏血管紧张素转换酶的新功能

期刊:Molecular and Cellular Endocrinology
影响因子:3.6
doi:10.1016/j.mce.2021.111257
Giani, Jorge F; Veiras, Luciana C; Shen, Justin Z Y; Bernstein, Ellen A; Cao, DuoYao; Okwan-Duodu, Derick; Khan, Zakir; Gonzalez-Villalobos, Romer A; Bernstein, Kenneth E
发表日期：2021
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Role of angiotensin-converting enzyme in myeloid cell immune responses

血管紧张素转换酶在髓系细胞免疫反应中的作用

期刊:Cellular & Molecular Biology Letters
影响因子:10.2
doi:10.1186/s11658-020-00225-w
Cao, Duo-Yao; Saito, Suguru; Veiras, Luciana C; Okwan-Duodu, Derick; Bernstein, Ellen A; Giani, Jorge F; Bernstein, Kenneth E; Khan, Zakir
细胞生物学
免疫/内分泌
发表日期：2020
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Overexpression of ACE in Myeloid Cells Increases Immune Effectiveness and Leads to a New Way of Considering Inflammation in Acute and Chronic Diseases

髓系细胞中ACE的过度表达增强了免疫效力，并为理解急慢性疾病中的炎症机制提供了一种新思路。

期刊:Current Hypertension Reports
影响因子:5.1
doi:10.1007/s11906-019-1008-x
Veiras, Luciana C; Cao, DuoYao; Saito, Suguru; Peng, Zhenzi; Bernstein, Ellen A; Shen, Justin Z Y; Koronyo-Hamaoui, Maya; Okwan-Duodu, Derick; Giani, Jorge F; Khan, Zakir; Bernstein, Kenneth E
炎症
炎症/感染
Immunology/Inflammation
细胞生物学
免疫/内分泌
发表日期：2020
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Overexpression of the C-domain of angiotensin-converting enzyme reduces melanoma growth by stimulating M1 macrophage polarization

血管紧张素转换酶C结构域的过度表达通过刺激M1型巨噬细胞极化来减少黑色素瘤的生长

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.RA118.006275
Khan, Zakir; Cao, Duo-Yao; Giani, Jorge F; Bernstein, Ellen A; Veiras, Luciana C; Fuchs, Sebastien; Wang, Yizhou; Peng, Zhenzi; Kalkum, Markus; Liu, George Y; Bernstein, Kenneth E
巨噬细胞
黑色素瘤
巨噬细胞
细胞生物学
免疫/内分泌
发表日期：2019
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Overexpression of myeloid angiotensin-converting enzyme (ACE) reduces atherosclerosis

髓系血管紧张素转换酶（ACE）的过度表达可降低动脉粥样硬化

期刊:Biochemical and Biophysical Research Communications
影响因子:2.2
doi:10.1016/j.bbrc.2019.10.078
Okwan-Duodu, Derick; Weiss, Daiana; Peng, Zhenzi; Veiras, Luciana C; Cao, Duo-Yao; Saito, Suguru; Khan, Zakir; Bernstein, Ellen A; Giani, Jorge F; Taylor, W Robert; Bernstein, Kenneth E
心血管
动脉粥样硬化
发表日期：2019
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Angiotensin-converting enzyme in innate and adaptive immunity

血管紧张素转换酶在先天性和适应性免疫中的作用

期刊:Nature Reviews Nephrology
影响因子:39.8
doi:10.1038/nrneph.2018.15
Bernstein, Kenneth E; Khan, Zakir; Giani, Jorge F; Cao, Duo-Yao; Bernstein, Ellen A; Shen, Xiao Z
免疫/内分泌
发表日期：2018
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