Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1
埃博拉病毒VP24靶向核转运蛋白α5上的独特NLS结合位点,从而选择性地与磷酸化STAT1的核输入竞争。
期刊:Cell Host & Microbe
影响因子:18.7
doi:10.1016/j.chom.2014.07.008
Xu, Wei; Edwards, Megan R; Borek, Dominika M; Feagins, Alicia R; Mittal, Anuradha; Alinger, Joshua B; Berry, Kayla N; Yen, Benjamin; Hamilton, Jennifer; Brett, Tom J; Pappu, Rohit V; Leung, Daisy W; Basler, Christopher F; Amarasinghe, Gaya K