日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of DC-174 as a Novel Hydroxamic Precandidate for the Development of an Oral Snakebite Treatment

鉴定出DC-174是一种新型羟肟酸类候选药物,可用于开发口服蛇咬伤治疗药物。

Chong, Daniel J W; Albulescu, Laura-Oana; Westhorpe, Adam; Clare, Rachel H; Marriott, Amy E; Woodley, Christopher M; Gunasekar, Ramachandran; Mosallam, Nada; Crittenden, Edouard; Stars, Emma; Dawson, Charlotte; Kool, Jeroen; Wilkinson, Mark C; Leung, Suet C; Berry, Neil G; Casewell, Nicholas R; O'Neill, Paul M

Predicting the Mechanical Properties of Supramolecular Gels

预测超分子凝胶的力学性能

Simpson, Jack D; Thomson, Lisa; Woodley, Christopher M; Wallace, Chloe M; Dietrich, Bart; Loch, Alex S; Adams, Dave J; Berry, Neil G

Potent Preorganized Pyrazolidine Cyclophilin D Inhibitors Prevent Mitochondrial and Organ Injury in a Mouse Pancreatitis Disease Model

强效预组织吡唑烷环孢素D抑制剂可预防小鼠胰腺炎疾病模型中的线粒体和器官损伤

Awais, Muhammad; Woodley, Christopher M; Guo, Liqun; Rogers, Michael; Kershaw, Neil; Zacharchenko, Thomas; Shore, Emma; Kattakayam, Arjun; Mukherjee, Rajarshi; Criddle, David N; Leung, Suet C; Lee, Heather; Burgess-McCann, Joshua; Luzyanin, Konstantin; Berry, Neil G; Antonyuk, Svetlana; Lian, Lu-Yun; Sutton, Robert; O'Neill, Paul M

Design, synthesis and modelling of photoreactive chemical probes for investigating target engagement of plasmepsin IX and X in Plasmodium falciparum

设计、合成和建模光反应化学探针,用于研究恶性疟原虫中疟原虫蛋白酶IX和X的靶标结合

Lisauskaitė, Monika; Nixon, Gemma L; Woodley, Christopher M; Berry, Neil G; Coninckx, Andy; Qie, L Charlie; Leung, Suet C; Taramelli, Donatella; Basilico, Nicoletta; Parapini, Silvia; Ward, Stephen A; Vadas, Oscar; Soldati-Favre, Dominique; Hong, W David; O'Neill, Paul M

Identification of 2-Aryl-Quinolone Inhibitors of Cytochrome bd and Chemical Validation of Combination Strategies for Respiratory Inhibitors against Mycobacterium tuberculosis

鉴定细胞色素bd的2-芳基喹诺酮抑制剂及抗结核分枝杆菌呼吸抑制剂组合策略的化学验证

Jeffreys, Laura N; Ardrey, Alison; Hafiz, Taghreed A; Dyer, Lauri-Anne; Warman, Ashley J; Mosallam, Nada; Nixon, Gemma L; Fisher, Nicholas E; Hong, W David; Leung, Suet C; Aljayyoussi, Ghaith; Bibby, Jaclyn; Almeida, Deepak V; Converse, Paul J; Fotouhi, Nader; Berry, Neil G; Nuermberger, Eric L; Upton, Anna M; O'Neill, Paul M; Ward, Stephen A; Biagini, Giancarlo A

Machine-Learning Prediction of Metal-Organic Framework Guest Accessibility from Linker and Metal Chemistry

利用机器学习方法,基于连接基团和金属化学预测金属有机框架客体分子的可及性

Pétuya, Rémi; Durdy, Samantha; Antypov, Dmytro; Gaultois, Michael W; Berry, Neil G; Darling, George R; Katsoulidis, Alexandros P; Dyer, Matthew S; Rosseinsky, Matthew J

Targeting the Ubiquinol-Reduction (Q(i)) Site of the Mitochondrial Cytochrome bc(1) Complex for the Development of Next Generation Quinolone Antimalarials

靶向线粒体细胞色素bc(1)复合物的泛醌还原(Q(i))位点以开发下一代喹诺酮类抗疟药

Amporndanai, Kangsa; Pinthong, Nattapon; O'Neill, Paul M; Hong, W David; Amewu, Richard K; Pidathala, Chandrakala; Berry, Neil G; Leung, Suet C; Ward, Stephen A; Biagini, Giancarlo A; Hasnain, S Samar; Antonyuk, Svetlana V

Metabolomic studies in the inborn error of metabolism alkaptonuria reveal new biotransformations in tyrosine metabolism

代谢组学研究揭示了先天性代谢缺陷——尿黑酸症中酪氨酸代谢的新生物转化过程

Norman, Brendan P; Davison, Andrew S; Hughes, Juliette H; Sutherland, Hazel; Wilson, Peter Jm; Berry, Neil G; Hughes, Andrew T; Milan, Anna M; Jarvis, Jonathan C; Roberts, Norman B; Ranganath, Lakshminarayan R; Bou-Gharios, George; Gallagher, James A

Amino Acid Residues Determine the Response of Flexible Metal-Organic Frameworks to Guests

氨基酸残基决定柔性金属有机框架对客体的响应

Yan, Yong; Carrington, Elliot J; Pétuya, Rémi; Whitehead, George F S; Verma, Ajay; Hylton, Rebecca K; Tang, Chiu C; Berry, Neil G; Darling, George R; Dyer, Matthew S; Antypov, Dmytro; Katsoulidis, Alexandros P; Rosseinsky, Matthew J

α-Methyl-α-phenylsuccinimide ameliorates neurodegeneration in a C. elegans model of TDP-43 proteinopathy

α-甲基-α-苯基琥珀酰亚胺可改善秀丽隐杆线虫TDP-43蛋白病模型中的神经退行性变。

Wong, Shi Quan; Pontifex, Matthew G; Phelan, Marie M; Pidathala, Chandra; Kraemer, Brian C; Barclay, Jeff W; Berry, Neil G; O'Neill, Paul M; Burgoyne, Robert D; Morgan, Alan