Alternative splice variants of DCLK1 mark cancer stem cells, promote self-renewal and drug-resistance, and can be targeted to inhibit tumorigenesis in kidney cancer
DCLK1的替代剪接变体可标记癌症干细胞,促进自我更新和耐药性,并可作为抑制肾癌肿瘤发生的靶点。
期刊:International Journal of Cancer
影响因子:4.7
doi:10.1002/ijc.31400
Ge, Yang; Weygant, Nathaniel; Qu, Dongfeng; May, Randal; Berry, William L; Yao, Jiannan; Chandrakesan, Parthasarathy; Zheng, Wei; Zhao, Lichao; Zhao, Karena L; Drake, Michael; Vega, Kenneth J; Bronze, Michael S; Tomasek, James J; An, Guangyu; Houchen, Courtney W
肿瘤
DCLK1
肿瘤免疫
细胞生物学
肾癌
CLK1
干细胞
发育与干细胞