日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Rapid Affinity and Microsomal Stability Ranking of Crude Mixture Libraries of Histone Deacetylase Inhibitors

组蛋白去乙酰化酶抑制剂粗提物库的快速亲和力和微粒体稳定性排序

Tyagarajan, Sriram; Andrews, Christine L; Beshore, Douglas C; Buevich, Alexei V; Curran, Patrick J; Dandliker, Peter; Greshock, Thomas J; Hoar, Jason; Kim, Alex; Karnachi, Prabha; Knemeyer, Ian; Kozlowski, Joseph; Liu, Jian; Maletic, Milana; Myers, Robert; Rada, Vanessa; Sha, Deyou; Sauvagnat, Berengere; Vachal, Petr; Wolkenberg, Scott; Yu, Wensheng; Yu, Younong; Krska, Shane W

Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases

呼吸道合胞病毒和人类亚肺病毒 RNA 依赖性 RNA 聚合酶上保守的变构抑制位点

Victoria A Kleiner #, Thierry O Fischmann #, John A Howe, Douglas C Beshore, Michael J Eddins, Yan Hou, Todd Mayhood, Daniel Klein, Debbie D Nahas, Bob J Lucas, He Xi, Edward Murray, Daphne Y Ma, Krista Getty, Rachel Fearns

Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor Interaction

重新定义组蛋白去乙酰化酶抑制剂药效团:高效且无锌辅因子相互作用

Beshore, Douglas C; Adam, Gregory C; Barnard, Richard J O; Burlein, Christine; Gallicchio, Steven N; Holloway, M Katharine; Krosky, Daniel; Lemaire, Wei; Myers, Robert W; Patel, Sangita; Plotkin, Michael A; Powell, David A; Rada, Vanessa; Cox, Christopher D; Coleman, Paul J; Klein, Daniel J; Wolkenberg, Scott E

OSIRIS-REx Contamination Control Strategy and Implementation

OSIRIS-REx污染控制策略及实施

Dworkin, J P; Adelman, L A; Ajluni, T; Andronikov, A V; Aponte, J C; Bartels, A E; Beshore, E; Bierhaus, E B; Brucato, J R; Bryan, B H; Burton, A S; Callahan, M P; Castro-Wallace, S L; Clark, B C; Clemett, S J; Connolly, H C Jr; Cutlip, W E; Daly, S M; Elliott, V E; Elsila, J E; Enos, H L; Everett, D F; Franchi, I A; Glavin, D P; Graham, H V; Hendershot, J E; Harris, J W; Hill, S L; Hildebrand, A R; Jayne, G O; Jenkens, R W Jr; Johnson, K S; Kirsch, J S; Lauretta, D S; Lewis, A S; Loiacono, J J; Lorentson, C C; Marshall, J R; Martin, M G; Matthias, L L; McLain, H L; Messenger, S R; Mink, R G; Moore, J L; Nakamura-Messenger, K; Nuth, J A 3rd; Owens, C V; Parish, C L; Perkins, B D; Pryzby, M S; Reigle, C A; Righter, K; Rizk, B; Russell, J F; Sandford, S A; Schepis, J P; Songer, J; Sovinski, M F; Stahl, S E; Thomas-Keprta, K; Vellinga, J M; Walker, M S

MK-7622: A First-in-Class M(1) Positive Allosteric Modulator Development Candidate

MK-7622:首创的M(1)正向变构调节剂候选药物

Beshore, Douglas C; N Di Marco, Christina; Chang, Ronald K; Greshock, Thomas J; Ma, Lei; Wittmann, Marion; Seager, Matthew A; Koeplinger, Kenneth A; Thompson, Charles D; Fuerst, Joy; Hartman, George D; Bilodeau, Mark T; Ray, William J; Kuduk, Scott D

Construction of 5,6-Ring Fused 2-Pyridones: An Effective Annulation Tactic Achieved in Water

5,6-环稠合2-吡啶酮的构建:一种在水中实现的有效环化策略

Smith, Amos B; Atasoylu, Onur; Beshore, Douglas C

The lyconadins: enantioselective total syntheses of (+)-lyconadin A and (-)-lyconadin B

狼毒素:(+)-狼毒素A和(-)-狼毒素B的对映选择性全合成

Beshore, Douglas C; Smith, Amos B 3rd