日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Protocol for analyzing immune cell infiltration in 3D pancreatic heterotypic spheroids composed of tumor cells and cancer-associated fibroblasts.

分析由肿瘤细胞和癌相关成纤维细胞组成的 3D 胰腺异型球体中免疫细胞浸润的方案。

期刊:STAR Protocols
影响因子:1.3
doi:10.1016/j.xpro.2026.104383
Thomas Bessede, Nadia Vezzio-Vie, Clara Freixinos, Nelly Pirot, Nathalie Bonnefoy, Celine Gongora, Christel Larbouret, Laurent Gros
细胞生物学
肿瘤细胞
成纤维细胞
发表日期：2026
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Robot-Assisted Cystoprostatectomy for Muscle-Invasive Bladder Cancer in a Patient With a Prior Simultaneous Pancreas-Kidney Transplantation

机器人辅助膀胱前列腺切除术治疗既往接受过胰肾联合移植的肌层浸润性膀胱癌患者

期刊:Case Reports in Transplantation
影响因子:
doi:10.1155/crit/9534770
Lonca, Laetitia; Beniac, Peter; Necsulescu, Andrei; Teixeira-Guerra, David; Parier, Bastien; Irani, Jacques; Ferlicot, Sophie; Bessede, Thomas; Snanoudj, Renaud; Lebacle, Cedric
肿瘤
肿瘤免疫
膀胱癌
发表日期：2026
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Reshaping the tumor microenvironment of cold soft-tissue sarcomas with anti-angiogenics: a phase 2 trial of regorafenib combined with avelumab

利用抗血管生成药物重塑冷软组织肉瘤的肿瘤微环境：瑞戈非尼联合阿维鲁单抗的 II 期临床试验

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-025-02278-9
Toulmonde, Maud; Guégan, Jean-Philippe; Spalato-Ceruso, Mariella; Valentin, Thibaud; Bahleda, Rastilav; Peyraud, Florent; Rey, Christophe; Kind, Michèle; Cantarel, Coralie; Bellera, Carine; Vanhersecke, Lucile; Bessede, Alban; Italiano, Antoine
肿瘤
血管生成
肿瘤免疫
肿瘤微环境
发表日期：2025
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Spatially resolved transcriptomics reveal the determinants of primary resistance to immunotherapy in NSCLC with mature tertiary lymphoid structures

空间分辨转录组学揭示了具有成熟三级淋巴结构的 NSCLC 对免疫治疗产生原发性耐药性的决定因素

期刊:Cell Reports Medicine
影响因子:11.7
doi:10.1016/j.xcrm.2025.101934
Florent Peyraud, Jean-Philippe Guégan, Christophe Rey, Oren Lara, Ophélie Odin, Marie Del Castillo, Lucile Vanhersecke, Jean-Michel Coindre, Emma Clot, Maxime Brunet, Thomas Grellety, Angélique Tasseel, Sylvestre Le Moulec, Robert J Johnston, Alban Bessede, Antoine Italiano0
免疫
发表日期：2025
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ATR inhibition potentiates FOLFIRINOX cytotoxic effect in models of pancreatic ductal adenocarcinoma by remodelling the tumour microenvironment

ATR抑制剂通过重塑肿瘤微环境，增强FOLFIRINOX在胰腺导管腺癌模型中的细胞毒性作用。

期刊:British Journal of Cancer
影响因子:6.4
doi:10.1038/s41416-024-02904-3
Marine Bruciamacchie ，Véronique Garambois # ，Nadia Vie # ，Thomas Bessede ，Henri-Alexandre Michaud ，Laure-Agnès Chepeaux ，Laurent Gros ，Nathalie Bonnefoy ，Mathilde Robin ，Dorian Brager ，Kevin Bigot ，Alexandre Evrard ，Philippe Pourquier ，Jacques Colinge ，Muriel Mathonnet ，Ismahane Belhabib ，Christine Jean ，Corinne Bousquet ，Pierre-Emmanuel Colombo ，Marta Jarlier ，Diégo Tosi ，Céline Gongora # ，Christel Larbouret #
肿瘤微环境
细胞生物学
肿瘤
毒理研究
肿瘤免疫
ATR
发表日期：2025
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Evaluation of a rapid fluorescence immunoassay for detecting Campylobacter antigens in stool samples

评估一种用于检测粪便样本中弯曲杆菌抗原的快速荧光免疫测定法

期刊:Gut Pathogens
影响因子:4
doi:10.1186/s13099-025-00686-4
Bénéjat, Lucie; Ducournau, Astrid; Gebhart, Juliette; Bessede, Emilie; Becker, Juergen; Jauvain, Marine; Lehours, Philippe
IF
免疫/内分泌
发表日期：2025
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Pembrolizumab in soft-tissue sarcomas with tertiary lymphoid structures: a phase 2 PEMBROSARC trial cohort

帕博利珠单抗在具有三级淋巴结构的软组织肉瘤中的应用：一项 2 期 PEMBROSARC 试验队列

期刊:Nature Medicine
影响因子:58.7
doi:10.1038/s41591-022-01821-3
A Italiano #, A Bessede #, M Pulido #, E Bompas, S Piperno-Neumann, C Chevreau, N Penel, F Bertucci, M Toulmonde, C Bellera, J P Guegan, C Rey, C Sautès-Fridman, A Bougoüin, C Cantarel, M Kind, M Spalato, B Dadone-Montaudie, F Le Loarer, J Y Blay, W H Fridman4
ARC
发表日期：2024
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Predictive value of tumor microenvironment on pathologic response to neoadjuvant chemotherapy in patients with undifferentiated pleomorphic sarcomas

肿瘤微环境对未分化多形性肉瘤患者新辅助化疗病理反应的预测价值

期刊:Journal of Hematology & Oncology
影响因子:40.4
doi:10.1186/s13045-024-01614-w
Guegan, Jean Philippe; El Ghazzi, Nathan; Vibert, Julien; Rey, Christophe; Vanhersecke, Lucile; Coindre, Jean Michel; Toulmonde, Maud; Spalato Ceruso, Mariella; Peyraud, Florent; Bessede, Alban; Italiano, Antoine
肿瘤
肿瘤微环境
肿瘤免疫
发表日期：2024
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Impact of metronomic trabectedin combined with low-dose cyclophosphamide on sarcoma microenvironment and correlation with clinical outcome: results from the TARMIC study

节拍式曲贝替定联合低剂量环磷酰胺对肉瘤微环境的影响及其与临床结局的相关性：TARMIC 研究结果

期刊:Molecular Cancer
影响因子:33.9
doi:10.1186/s12943-024-01942-y
Sun, Cheng-Ming; Toulmonde, Maud; Spalato-Ceruso, Mariella; Peyraud, Florent; Bessede, Alban; Kind, Michèle; Cousin, Sophie; Buy, Xavier; Palussiere, Jean; Bougouin, Antoine; Sautès-Fridman, Catherine; Fridman, Hervé Wolf; Pulido, Marina; Italiano, Antoine
发表日期：2024
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Reshaping the tumor microenvironment of cold soft-tissue sarcomas with oncolytic viral therapy: a phase 2 trial of intratumoral JX-594 combined with avelumab and low-dose cyclophosphamide

利用溶瘤病毒疗法重塑冷软组织肉瘤的肿瘤微环境：一项瘤内注射 JX-594 联合阿维鲁单抗和低剂量环磷酰胺的 II 期临床试验

期刊:Molecular Cancer
影响因子:33.9
doi:10.1186/s12943-024-01946-8
Toulmonde, Maud; Guegan, Jean-Philippe; Spalato-Ceruso, Mariella; Peyraud, Florent; Kind, Michèle; Vanhersecke, Lucile; Le Loarer, François; Perret, Raul; Cantarel, Coralie; Bellera, Carine; Bessede, Alban; Italiano, Antoine
微生物学
肿瘤
肿瘤微环境
肿瘤免疫
发表日期：2024
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