日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Adenosine A2B Receptor Promotes Tumor Progression and Metastases in Undifferentiated Pleomorphic Sarcoma

腺苷A2B受体促进未分化多形性肉瘤的肿瘤进展和转移

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-24-3934
Spalato Ceruso, Mariella; Guégan, Jean-Philippe; Bourdon, Aurélien; Chaire, Vanessa; Valverde Timana, Yanina; Giese, Alban; Rey, Christophe; Bessede, Alban; Perret, Raul; Vanhersecke, Lucile; Velasco, Valérie; Finetti, Pascal; Bertucci, François; Verbeke, Stéphanie; Italiano, Antoine
信号转导
肿瘤
肿瘤免疫
发表日期：2026
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Reshaping the tumor microenvironment of cold soft-tissue sarcomas with anti-angiogenics: a phase 2 trial of regorafenib combined with avelumab

利用抗血管生成药物重塑冷软组织肉瘤的肿瘤微环境：瑞戈非尼联合阿维鲁单抗的 II 期临床试验

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-025-02278-9
Toulmonde, Maud; Guégan, Jean-Philippe; Spalato-Ceruso, Mariella; Valentin, Thibaud; Bahleda, Rastilav; Peyraud, Florent; Rey, Christophe; Kind, Michèle; Cantarel, Coralie; Bellera, Carine; Vanhersecke, Lucile; Bessede, Alban; Italiano, Antoine
肿瘤
血管生成
肿瘤免疫
肿瘤微环境
发表日期：2025
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Predictive value of tumor microenvironment on pathologic response to neoadjuvant chemotherapy in patients with undifferentiated pleomorphic sarcomas

肿瘤微环境对未分化多形性肉瘤患者新辅助化疗病理反应的预测价值

期刊:Journal of Hematology & Oncology
影响因子:40.4
doi:10.1186/s13045-024-01614-w
Guegan, Jean Philippe; El Ghazzi, Nathan; Vibert, Julien; Rey, Christophe; Vanhersecke, Lucile; Coindre, Jean Michel; Toulmonde, Maud; Spalato Ceruso, Mariella; Peyraud, Florent; Bessede, Alban; Italiano, Antoine
肿瘤
肿瘤微环境
肿瘤免疫
发表日期：2024
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Impact of metronomic trabectedin combined with low-dose cyclophosphamide on sarcoma microenvironment and correlation with clinical outcome: results from the TARMIC study

节拍式曲贝替定联合低剂量环磷酰胺对肉瘤微环境的影响及其与临床结局的相关性：TARMIC 研究结果

期刊:Molecular Cancer
影响因子:33.9
doi:10.1186/s12943-024-01942-y
Sun, Cheng-Ming; Toulmonde, Maud; Spalato-Ceruso, Mariella; Peyraud, Florent; Bessede, Alban; Kind, Michèle; Cousin, Sophie; Buy, Xavier; Palussiere, Jean; Bougouin, Antoine; Sautès-Fridman, Catherine; Fridman, Hervé Wolf; Pulido, Marina; Italiano, Antoine
发表日期：2024
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Reshaping the tumor microenvironment of cold soft-tissue sarcomas with oncolytic viral therapy: a phase 2 trial of intratumoral JX-594 combined with avelumab and low-dose cyclophosphamide

利用溶瘤病毒疗法重塑冷软组织肉瘤的肿瘤微环境：一项瘤内注射 JX-594 联合阿维鲁单抗和低剂量环磷酰胺的 II 期临床试验

期刊:Molecular Cancer
影响因子:33.9
doi:10.1186/s12943-024-01946-8
Toulmonde, Maud; Guegan, Jean-Philippe; Spalato-Ceruso, Mariella; Peyraud, Florent; Kind, Michèle; Vanhersecke, Lucile; Le Loarer, François; Perret, Raul; Cantarel, Coralie; Bellera, Carine; Bessede, Alban; Italiano, Antoine
微生物学
肿瘤
肿瘤微环境
肿瘤免疫
发表日期：2024
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Identification of microenvironment features associated with primary resistance to anti-PD-1/PD-L1 + antiangiogenesis in gastric cancer through spatial transcriptomics and plasma proteomics.

通过空间转录组学和血浆蛋白质组学鉴定与胃癌中抗PD-1/PD-L1+抗血管生成原发性耐药相关的微环境特征

期刊:Molecular Cancer
影响因子:33.9
doi:10.1186/s12943-024-02092-x
Cousin Sophie, Guégan Jean-Philippe, Shitara Kohei, Palmieri Lola Jade, Metges Jean Philippe, Pernot Simon, Fukuoka Shota, Koyama Shohei, Nishikawa Hiroyoshi, Bellera Carine A, Adenis Antoine, Gomez-Roca Carlos A, Cassier Philippe Alexandre, Hollebecque Antoine, Cantarel Coralie, Kind Michèle, Soubeyran Isabelle, Vanhersecke Lucile, Bessede Alban, Italiano Antoine
心血管
胃癌
血管生成
发表日期：2024
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Deciphering the correlation between metabolic activity through 18F-FDG-PET/CT and immune landscape in soft-tissue sarcomas: an insight from the NEOSARCOMICS study

通过 18F-FDG-PET/CT 解读软组织肉瘤代谢活性与免疫图谱之间的相关性：来自 NEOSARCOMICS 研究的启示

期刊:Biomarker Research
影响因子:11.5
doi:10.1186/s40364-023-00552-y
Crombé, Amandine; Bertolo, Frédéric; Vanhersecke, Lucile; Guegan, Jean-Philippe; Bessede, Alban; Perret, Raul; Le Loarer, François; Chaire, Vanessa; Coindre, Jean-Michel; Lucchesi, Carlo; Italiano, Antoine
代谢
ARC
免疫/内分泌
发表日期：2024
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Analysis of PD1, LAG3, TIGIT, and TIM3 expression in human lung adenocarcinoma reveals a 25-gene signature predicting immunotherapy response

对人肺腺癌中PD1、LAG3、TIGIT和TIM3表达的分析揭示了一个包含25个基因的特征谱，该特征谱可预测免疫治疗反应。

期刊:Cell Reports Medicine
影响因子:10.6
doi:10.1016/j.xcrm.2024.101831
Guégan, Jean-Philippe; Peyraud, Florent; Dadone-Montaudie, Bérengère; Teyssonneau, Diego; Palmieri, Lola-Jade; Clot, Emma; Cousin, Sophie; Roubaud, Guilhem; Cabart, Mathilde; Leroy, Laura; Lebreton, Coriolan; Rey, Christophe; Lara, Oren; Odin, Ophélie; Brunet, Maxime; Vanhersecke, Lucile; Gruyters, Ezogelin Oflazoglu; Achour, Ikbel; Belcaid, Leila; Le Moulec, Sylvestre; Grellety, Thomas; Bessede, Alban; Italiano, Antoine
肿瘤
TIM
肿瘤免疫
LAG3
TIGIT
免疫/内分泌
发表日期：2024
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TROP2 Is Associated with Primary Resistance to Immune Checkpoint Inhibition in Patients with Advanced Non-Small Cell Lung Cancer

TROP2与晚期非小细胞肺癌患者对免疫检查点抑制剂的原发性耐药相关

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-23-2566
Bessede, Alban; Peyraud, Florent; Besse, Benjamin; Cousin, Sophie; Cabart, Mathilde; Chomy, François; Rey, Christophe; Lara, Oren; Odin, Ophélie; Nafia, Imane; Vanhersecke, Lucile; Barlesi, Fabrice; Guégan, Jean-Philippe; Italiano, Antoine
Checkpoint
肺癌
肿瘤
肿瘤免疫
细胞生物学
免疫/内分泌
发表日期：2024
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AT-0174, a novel dual IDO1/TDO2 enzyme inhibitor, synergises with temozolomide to improve survival in an orthotopic mouse model of glioblastoma

AT-0174 是一种新型的双重 IDO1/TDO2 酶抑制剂，与替莫唑胺联用可提高胶质母细胞瘤原位小鼠模型的生存率。

期刊:BMC Cancer
影响因子:3.4
doi:10.1186/s12885-024-12631-w
Bickerdike, Michael J; Nafia, Imane; Bessede, Alban; Chen, Cheng-Bang; Wangpaichitr, Medhi
细胞生物学
IDO
发表日期：2024
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