日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Inhibition of fatty acid synthase enhances therapeutic efficacy and delays acquired resistance to BRAF-targeted therapy in colorectal cancer

抑制脂肪酸合成酶可增强结直肠癌对BRAF靶向治疗的疗效并延缓其获得性耐药。

Geisen, Mariah E; Tessmann, Josiane W; Kelson, Courtney O; He, Daheng; Wang, Chi; Faisal, Abu Saleh Mosa; Beswick, Ellen J; Baca, Yasmine; Rock, Stephanie; Kolesar, Jill M; Zaytseva, Yekaterina Y

MK2 Inhibition as a Novel Treatment for Fibrosis in Primary Sclerosing Cholangitis via an IL-22-Dependent Mechanism

MK2抑制剂通过IL-22依赖性机制治疗原发性硬化性胆管炎纤维化的新方法

Howe, Cody S; Beswick, Ellen J

MK2 Inhibition in CD4+ T Cells Protects Against IFNγ and IL-17A, Chronic Inflammation, and Fibrosis in Inflammatory Bowel Disease Models

在炎症性肠病模型中,CD4+ T细胞中的MK2抑制可抵抗IFNγ和IL-17A、慢性炎症和纤维化。

Howe, Cody S; Chulkina, Marina; Syrcle, Ryan; McAninch, Christina; McAninch, Steven; Pinchuk, Irina V; Beswick, Ellen J

MK2 drives progression of pancreas and colon cancers by suppressing CD8(+) T cell cytotoxic function and is a potential immunotherapy target

MK2通过抑制CD8(+) T细胞的细胞毒性功能促进胰腺癌和结肠癌的进展,是一种潜在的免疫治疗靶点。

Jacenik, Damian; Lebish, Eric J; Beswick, Ellen J

The clinical relevance of the adhesion G protein-coupled receptor F5 for human diseases and cancers

黏附性G蛋白偶联受体F5在人类疾病和癌症中的临床意义

Jacenik, Damian; Hikisz, Pawel; Beswick, Ellen J; Fichna, Jakub

MK2 Promotes the Development and Progression of Pancreatic Neuroendocrine Tumors Mediated by Macrophages and Metabolomic Factors

MK2通过巨噬细胞和代谢组学因子促进胰腺神经内分泌肿瘤的发生发展

Jacenik, Damian; Lebish, Eric J; Beswick, Ellen J

Translational challenges in pancreatic neuroendocrine tumor immunotherapy

胰腺神经内分泌肿瘤免疫治疗的转化挑战

Egal, Erika Said Abu; Jacenik, Damian; Soares, Heloisa Prado; Beswick, Ellen J

G-CSF in tumors: Aggressiveness, tumor microenvironment and immune cell regulation

G-CSF在肿瘤中的作用:侵袭性、肿瘤微环境和免疫细胞调控

Karagiannidis, Ioannis; Salataj, Eralda; Said Abu Egal, Erika; Beswick, Ellen J

Granulocyte colony-stimulating factor promotes an aggressive phenotype of colon and breast cancer cells with biochemical changes investigated by single-cell Raman microspectroscopy and machine learning analysis

粒细胞集落刺激因子促进结肠癌和乳腺癌细胞的侵袭性表型,其生化变化可通过单细胞拉曼显微光谱和机器学习分析进行研究。

Zhang, Wei; Karagiannidis, Ioannis; Van Vliet, Eliane De Santana; Yao, Ruoxin; Beswick, Ellen J; Zhou, Anhong

The MK2 pathway is linked to G-CSF, cytokine production and metastasis in gastric cancer: a novel intercorrelation analysis approach

MK2通路与胃癌中的G-CSF、细胞因子产生和转移相关:一种新的相互关联分析方法

Qeadan, Fares; Bansal, Pranshu; Hanson, Joshua A; Beswick, Ellen J