日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Microbiota encoded fatty-acid metabolism expands tuft cells to protect tissues homeostasis during Clostridioides difficile infection in the large intestine

大肠艰难梭菌感染期间,微生物编码的脂肪酸代谢扩张簇细胞以保护组织稳态

Tasia D Kellogg, Simona Ceglia, Benedikt M Mortzfeld, Abigail L Zeamer, Sage E Foley, Doyle V Ward, Shakti K Bhattarai, Beth A McCormick, Andrea Reboldi, Vanni Bucci

Bacteroides Fragilis in the gut microbiomes of Alzheimer's disease activates microglia and triggers pathogenesis in neuronal C/EBPβ transgenic mice

阿尔茨海默病肠道微生物群中的脆弱拟杆菌激活小胶质细胞并引发神经元 C/EBPβ 转基因小鼠的发病机制

Yiyuan Xia #, Yifan Xiao #, Zhi-Hao Wang, Xia Liu, Ashfaqul M Alam, John P Haran, Beth A McCormick, Xiji Shu, Xiaochuan Wang, Keqiang Ye

Development of ADS051, an oral, gut-restricted, small molecule neutrophil modulator for the treatment of neutrophil-mediated inflammatory diseases

开发 ADS051,一种口服、肠道限制的小分子中性粒细胞调节剂,用于治疗中性粒细胞介导的炎症疾病

Christopher K Murphy, Bharat Dixit, Frederick B Oleson, Roland E Dolle, Ronald Farquhar, Beth A McCormick

The epithelial-specific ER stress sensor ERN2/IRE1β enables host-microbiota crosstalk to affect colon goblet cell development

上皮特异性内质网应激传感器 ERN2/IRE1β 可使宿主-微生物群串扰影响结肠杯状细胞的发育

Michael J Grey, Heidi De Luca, Doyle V Ward, Irini Am Kreulen, Katlynn Bugda Gwilt, Sage E Foley, Jay R Thiagarajah, Beth A McCormick, Jerrold R Turner, Wayne I Lencer

Dietary manipulation of the gut microbiome in inflammatory bowel disease patients: Pilot study

炎症性肠病患者肠道微生物群的饮食控制:初步研究

Barbara Olendzki, Vanni Bucci, Caitlin Cawley, Rene Maserati, Margaret McManus, Effie Olednzki, Camilla Madziar, David Chiang, Doyle V Ward, Randall Pellish, Christine Foley, Shakti Bhattarai, Beth A McCormick, Ana Maldonado-Contreras

Microcin MccI47 selectively inhibits enteric bacteria and reduces carbapenem-resistant Klebsiella pneumoniae colonization in vivo when administered via an engineered live biotherapeutic

Microcin MccI47 通过工程活生物治疗药物给药时,可选择性抑制肠道细菌并减少体内耐卡巴培南肺炎克雷伯菌的定植

Benedikt M Mortzfeld, Jacob D Palmer, Shakti K Bhattarai, Haley L Dupre, Regino Mercado-Lubio, Mark W Silby, Corinna Bang, Beth A McCormick, Vanni Bucci

IFNγ regulates NAD+ metabolism to promote the respiratory burst in human monocytes

IFNγ调节NAD+代谢,促进人单核细胞的呼吸爆发。

Katelyn J McCann ,Stephen M Christensen ,Devon H Colby ,Peter J McGuire ,Ian A Myles ,Christa S Zerbe ,Clifton L Dalgard ,Gauthaman Sukumar ,Warren J Leonard ,Beth A McCormick ,Steven M Holland

Microbial Metabolites Orchestrate a Distinct Multi-Tiered Regulatory Network in the Intestinal Epithelium That Directs P-Glycoprotein Expression

微生物代谢物在肠道上皮中协调独特的多层调节网络,指导 P-糖蛋白的表达

Sage E Foley, Michael J Dente, Xuqiu Lei, Benjamin F Sallis, Ethan B Loew, Mario Meza-Segura, Katherine A Fitzgerald, Beth A McCormick

Differential effects of Akkermansia-enriched fecal microbiota transplant on energy balance in female mice on high-fat diet

富含 Akkermansia 的粪便微生物群移植对高脂饮食雌性小鼠能量平衡的不同影响

Kalpana D Acharya, Randall H Friedline, Doyle V Ward, Madeline E Graham, Lauren Tauer, Doris Zheng, Xiaodi Hu, Willem M de Vos, Beth A McCormick, Jason K Kim, Marc J Tetel

Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells

菌群失调通过促进髓系细胞中先天免疫接头蛋白STING的泛素化和积累,加剧结肠炎。

Liraz Shmuel-Galia ,Fiachra Humphries ,Xuqiu Lei ,Simona Ceglia ,Ruth Wilson ,Zhaozhao Jiang ,Natalia Ketelut-Carneiro ,Sage E Foley ,Susanne Pechhold ,JeanMarie Houghton ,Khaja Muneeruddin ,Scott A Shaffer ,Beth A McCormick ,Andrea Reboldi ,Doyle Ward ,Ann Marshak-Rothstein ,Katherine A Fitzgerald