日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Thrombopoietin Receptor Agonists for Thrombocytopenia in Pediatric Hematologic Malignancies

血小板生成素受体激动剂治疗儿童血液系统恶性肿瘤引起的血小板减少症

Marinoff, Amanda E; Thrall, Allyson; Aaronson, Kathryn; Braun, Benjamin S; Castellanos, Maria; Chu, Julia; Hermiston, Michelle; Huang, Benjamin J; Levinson, Anya; Southworth, Erica; Winger, Beth Apsel; Olshen, Adam; Stieglitz, Elliot

Integration of Genomic Sequencing Drives Therapeutic Targeting of PDGFRA in T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma

基因组测序的整合推动了针对T细胞急性淋巴细胞白血病/淋巴母细胞淋巴瘤中PDGFRA的治疗靶向治疗。

Jonathan Paolino # ,Boris Dimitrov # ,Beth Apsel Winger ,Angelica Sandoval-Perez ,Amith Vikram Rangarajan ,Nicole Ocasio-Martinez ,Harrison K Tsai ,Yuting Li ,Amanda L Robichaud ,Delan Khalid ,Charlie Hatton ,Riaz Gillani ,Petri Polonen ,Anthony Dilig ,Giacomo Gotti ,Julia Kavanagh ,Asmani A Adhav ,Sean Gow ,Jonathan Tsai ,Yen Der Li ,Benjamin L Ebert ,Eliezer M Van Allen ,Jacob Bledsoe ,Annette S Kim ,Sarah K Tasian ,Stacy L Cooper ,Todd M Cooper ,Nobuko Hijiya ,Maria Luisa Sulis ,Neerav N Shukla ,Jeffrey A Magee ,Charles G Mullighan ,Michael J Burke ,Marlise R Luskin ,Brenton G Mar ,Matthew P Jacobson ,Marian H Harris ,Kimberly Stegmaier ,Andrew E Place ,Yana Pikman

Correction to "Assessing the Activation of Tyrosine Kinase KIT through Free Energy Calculations"

对“通过自由能计算评估酪氨酸激酶KIT的活化”一文的更正

Sandoval-Pérez, Angélica; Winger, Beth Apsel; Jacobson, Matthew P

Assessing the Activation of Tyrosine Kinase KIT through Free Energy Calculations

通过自由能计算评估酪氨酸激酶KIT的激活

Sandoval-Pérez, Angélica; Winger, Beth Apsel; Jacobson, Matthew P

Quantification of N, N' N"-triethylenethiophosphoramide, N, N"-triethylenephosphoramide, cyclophosphamide, and 4-hydroxy-cyclophosphamide in microvolume human plasma to support neonatal and pediatric drug studies

微量人血浆中N,N'N''-三乙烯硫代磷酰胺、N,N''-三乙烯磷酰胺、环磷酰胺和4-羟基环磷酰胺的定量分析,以支持新生儿和儿科药物研究

Huang, Liusheng; Winger, Beth Apsel; Cheah, Vincent; Gingrich, David; Marzan, Florence; Lu, Ying; Cooper, Jennifer C; Aweeka, Francesca; Long-Boyle, Janel

Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory, or High-Risk Leukemias: A Report from the LEAP Consortium

针对复发性、难治性或高风险白血病儿童患者的匹配靶向治疗:LEAP 联盟的报告

Yana Pikman, Sarah K Tasian, Maria Luisa Sulis, Kristen Stevenson, Traci M Blonquist, Beth Apsel Winger, Todd M Cooper, Melinda Pauly, Kelly W Maloney, Michael J Burke, Patrick A Brown, Nathan Gossai, Jennifer L McNeer, Neerav N Shukla, Peter D Cole, Justine M Kahn, Jing Chen, Matthew J Barth, Jeffr

Assessment of a Model-Informed Precision Dosing Platform Use in Routine Clinical Care for Personalized Busulfan Therapy in the Pediatric Hematopoietic Cell Transplantation (HCT) Population

评估基于模型的精准给药平台在儿科造血干细胞移植(HCT)人群个性化白消安治疗常规临床护理中的应用

Shukla, Praveen; Goswami, Srijib; Keizer, Ron J; Winger, Beth Apsel; Kharbanda, Sandhya; Dvorak, Christopher C; Long-Boyle, Janel

Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

mTOR 活性位点抑制剂靶向雷帕霉素耐药的 mTORC1 和 mTORC2 输出

Morris E Feldman, Beth Apsel, Aino Uotila, Robbie Loewith, Zachary A Knight, Davide Ruggero, Kevan M Shokat

Discovery of drug-resistant and drug-sensitizing mutations in the oncogenic PI3K isoform p110 alpha

发现致癌 PI3K 亚型 p110 alpha 中的耐药和药物敏感突变

Eli R Zunder, Zachary A Knight, Benjamin T Houseman, Beth Apsel, Kevan M Shokat

Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases

靶向多药理学:酪氨酸和磷酸肌醇激酶双重抑制剂的发现

Beth Apsel, Jimmy A Blair, Beatriz Gonzalez, Tamim M Nazif, Morri E Feldman, Brian Aizenstein, Randy Hoffman, Roger L Williams, Kevan M Shokat, Zachary A Knight