日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Characterization of humoral and cellular immunity induced by mRNA vaccines expressing norovirus VP1 proteins in mice and NHPs.

对表达诺如病毒VP1蛋白的mRNA疫苗在小鼠和非人灵长类动物中诱导的体液免疫和细胞免疫进行表征。

Wei Jiajie, Bystol Karin, Alabanza Leah, Lim Shuhui, Greig Jamie, Gopal Pooja, Reyes Ballista Judith M, Galli Jennifer D, Warren Christopher, Swartz Andrew, David Courtney, Jeong Uijin, Gonzalez-Fernandez Estibaliz, DeWitt Lizzy Aurora, Go Gwenny, Lago Athena, Radcliffe Scott, May Fulton Corey D, Shen Pamela, Fridman Arthur, Gaspar John, Pirrone Amanda, Wen Zhiyun, O'Donnell Gregory, Austin Lauren, McKenney David, Krosky Paula, Liu Yaping, Bett Andrew J, Zhang Lan

Modified mRNA/lipid nanoparticle-based vaccines expressing respiratory syncytial virus F protein variants are immunogenic and protective in rodent models of RSV infection

表达呼吸道合胞病毒F蛋白变体的修饰型mRNA/脂质纳米颗粒疫苗在RSV感染的啮齿动物模型中具有免疫原性和保护作用。

Espeseth, Amy S; Cejas, Pedro J; Citron, Michael P; Wang, Dai; DiStefano, Daniel J; Callahan, Cheryl; Donnell, Gregory O'; Galli, Jennifer D; Swoyer, Ryan; Touch, Sinoeun; Wen, Zhiyun; Antonello, Joseph; Zhang, Lan; Flynn, Jessica A; Cox, Kara S; Freed, Daniel C; Vora, Kalpit A; Bahl, Kapil; Latham, Andrew H; Smith, Jeffrey S; Gindy, Marian E; Ciaramella, Giuseppe; Hazuda, Daria; Shaw, Christine A; Bett, Andrew J

Immunogenicity and safety of an investigational tetravalent recombinant subunit vaccine for dengue: results of a Phase I randomized clinical trial in flavivirus-naïve adults

一种在研四价重组亚单位登革热疫苗的免疫原性和安全性:一项针对未感染过黄病毒的成年人的I期随机临床试验结果

Manoff, Susan B; Sausser, Michele; Falk Russell, Amy; Martin, Jason; Radley, David; Hyatt, Donna; Roberts, Christine C; Lickliter, Jason; Krishnarajah, Janakan; Bett, Andrew; Dubey, Sheri; Finn, Tyler; Coller, Beth-Ann

Antibody responses to crucial functional epitopes as a novel approach to assess immunogenicity of vaccine adjuvants

针对关键功能表位的抗体反应是评估疫苗佐剂免疫原性的一种新方法

Awasthi, Sita; Hook, Lauren M; Swaminathan, Gokul; Cairns, Tina M; Brooks, Benjamin; Smith, Jeffrey S; Ditto, Noah T; Gindy, Marian E; Bett, Andrew J; Espeseth, Amy S; Cohen, Gary H; Friedman, Harvey M

Functionally inactivated dominant viral antigens of human cytomegalovirus delivered in replication incompetent adenovirus type 6 vectors as vaccine candidates

功能性灭活的人巨细胞病毒主要病毒抗原,以复制缺陷型6型腺病毒载体递送,作为候选疫苗。

Tang, Aimin; Freed, Daniel C; Li, Fengsheng; Meschino, Steve; Prokop, Michael; Bett, Andrew; Casimiro, Danilo; Wang, Dai; Fu, Tong-Ming

A Rapid and Improved Method to Generate Recombinant Dengue Virus Vaccine Candidates

一种快速改进的重组登革病毒候选疫苗制备方法

Govindarajan, Dhanasekaran; Guan, Liming; Meschino, Steven; Fridman, Arthur; Bagchi, Ansu; Pak, Irene; ter Meulen, Jan; Casimiro, Danilo R; Bett, Andrew J

Transcriptional profiling of vaccine-induced immune responses in humans and non-human primates

人类和非人灵长类动物疫苗诱导免疫反应的转录组分析

Wang, I-Ming; Bett, Andrew J; Cristescu, Razvan; Loboda, Andrey; ter Meulen, Jan

Low-dose penile SIVmac251 exposure of rhesus macaques infected with adenovirus type 5 (Ad5) and then immunized with a replication-defective Ad5-based SIV gag/pol/nef vaccine recapitulates the results of the phase IIb step trial of a similar HIV-1 vaccine

对感染腺病毒5型(Ad5)的恒河猴进行低剂量阴茎SIVmac251暴露,随后接种基于复制缺陷型Ad5的SIV gag/pol/nef疫苗,结果与类似HIV-1疫苗的IIb期试验结果一致。

Qureshi, Huma; Ma, Zhong-Min; Huang, Ying; Hodge, Gregory; Thomas, Michael A; DiPasquale, Janet; DeSilva, Veronique; Fritts, Linda; Bett, Andrew J; Casimiro, Danilo R; Shiver, John W; Robert-Guroff, Marjorie; Robertson, Michael N; McChesney, Michael B; Gilbert, Peter B; Miller, Christopher J

Comparative analysis of immune responses induced by vaccination with SIV antigens by recombinant Ad5 vector or plasmid DNA in rhesus macaques

比较分析用重组Ad5载体或质粒DNA接种SIV抗原后恒河猴的免疫反应

Hirao, Lauren A; Wu, Ling; Satishchandran, Abhishek; Khan, Amir S; Draghia-Akli, Ruxandra; Finnefrock, Adam C; Bett, Andrew J; Betts, Michael R; Casimiro, Danilo R; Sardesai, Niranjan Y; Kim, J Joseph; Shiver, John W; Weiner, David B

Distinct expression profiles of Notch-1 protein in human solid tumors: Implications for development of targeted therapeutic monoclonal antibodies.

Notch-1 蛋白在人类实体瘤中的独特表达谱:对靶向治疗性单克隆抗体开发的意义

Li Yuan, Burns Janine A, Cheney Carol A, Zhang Ningyan, Vitelli Salvatore, Wang Fubao, Bett Andrew, Chastain Michael, Audoly Laurent P, Zhang Zhi-Qiang