日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Disruption of hippocampal mitochondrial function underlies opioid-induced postoperative cognitive dysfunction in aged rats

老年大鼠阿片类药物诱发的术后认知功能障碍的根本原因是海马线粒体功能紊乱。

Muscat, Stephanie M; Deems, Nicholas P; Alvarez, Bryan D; Butler, Michael J; Gonzalez Olmo, Brigitte M; Kolonay, Dominic W; Sanders, Hannah F; Scaria, Emmanuel A; Mackey-Alfonso, Sabrina E; Blackwell, Jade A; DeMarsh, James W; Bettes, Menaz N; Quach, Tam T; Cortese, Giuseppe P; Glasper, Erica R; Leuner, Benedetta; Baskin, Kedryn K; Barrientos, Ruth M

Obesity-associated memory impairment and neuroinflammation precede widespread peripheral perturbations in aged rats

肥胖相关的记忆障碍和神经炎症先于老年大鼠广泛的外周紊乱出现。

Butler, Michael J; Muscat, Stephanie M; Caetano-Silva, Maria Elisa; Shrestha, Akriti; Olmo, Brigitte M González; Mackey-Alfonso, Sabrina E; Massa, Nashali; Alvarez, Bryan D; Blackwell, Jade A; Bettes, Menaz N; DeMarsh, James W; McCusker, Robert H; Allen, Jacob M; Barrientos, Ruth M

Ligature-induced periodontitis in a transgenic mouse model of Alzheimer's disease dysregulates neuroinflammation, exacerbates cognitive impairment, and accelerates amyloid pathology.

在阿尔茨海默病转基因小鼠模型中,结扎诱导的牙周炎会扰乱神经炎症,加剧认知障碍,并加速淀粉样蛋白病理的发生

Jimenez-Harrison Daniela M, Butler Michael J, Ijaz Haanya, Alsabbagh Rami, Bettes Menaz N, DeMarsh James W, Mackey-Alfonso Sabrina E, Muscat Stephanie M, Alvarez Bryan D, Blackwell Jade A, Taylor Ashton, Jantsch Jeferson, Sanchez Andrew A, Peters Sarah B, Barrientos Ruth M

Post-operative cognitive dysfunction is exacerbated by high-fat diet via TLR4 and prevented by dietary DHA supplementation

高脂饮食通过 TLR4 途径加剧术后认知功能障碍,而膳食补充 DHA 则可预防该障碍。

Muscat, Stephanie M; Butler, Michael J; Bettes, Menaz N; DeMarsh, James W; Scaria, Emmanuel A; Deems, Nicholas P; Barrientos, Ruth M

Short-term high-fat diet consumption impairs synaptic plasticity in the aged hippocampus via IL-1 signaling

短期高脂饮食会通过IL-1信号通路损害老年海马体的突触可塑性。

González Olmo, Brigitte M; Bettes, Menaz N; DeMarsh, James W; Zhao, Fangli; Askwith, Candice; Barrientos, Ruth M