日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A phase 1 study of berzosertib (M6620, VX-970) in combination with cisplatin and radiation in patients with locally advanced head and neck squamous cell carcinoma (ETCTN 9950)

一项针对局部晚期头颈部鳞状细胞癌患者的 1 期研究,评估 berzosertib (M6620, VX-970) 与顺铂和放射治疗的疗效 (ETCTN 9950)

Bhatia, Aarti; Chen, Zhengjia; Zhang, Yuji; Bruce, Justine Yang; Arnold, Susanne; Kaur, Varinder; Riess, Jonathan W; Fenton, Moon; Burtness, Barbara; Saba, Nabil F; Tara, Harold; Steuer, Conor E; Shin, Dong M; Wasp, Garrett; Davis, Thomas H; Patel, Malini; Schmitz, John C; Bhateja, Priyanka; Diavolitsis, Virginia; Zandberg, Dan P; Mitchell, Darrion L; Kiesel, Brian F; Kunos, Charles; Gore, Steven D; Carducci, Michael; Beumer, Jan H; Owonikoko, Taofeek K

A phase 1 study of the amino acid modulator pegcrisantaspase and venetoclax for relapsed or refractory acute myeloid leukemia

一项针对复发或难治性急性髓系白血病的氨基酸调节剂pegcrisantaspase和venetoclax的I期研究

Liu, Yuchen; Bollino, Dominique R; Bah, Osman M; Strovel, Erin T; Le, Tien V; Zarrabi, Jinoos; Philip, Sunita; Lapidus, Rena G; Baer, Maria R; Niyongere, Sandrine; Duong, Vu H; Dougherty, Christine C; Beumer, Jan H; Caprinolo, Katherine D; Kamangar, Farin; Emadi, Ashkan

Letrozole, abemaciclib and metformin in endometrial cancer: a non-randomized phase 2 trial

来曲唑、阿贝西利和二甲双胍治疗子宫内膜癌:一项非随机 II 期试验

Konstantinopoulos, Panagiotis A; Zhou, Ningxuan; Penson, Richard T; Le, Tien V; Campos, Susana; Krasner, Carolyn; Wright, Alexi A; Porter, Rebecca; Horowitz, Neil; Bouberhan, Sara; Liu, Joyce F; Hindenach, Sarah; Sawyer, Hannah; Koppermann, Lani; Hayes, Martin; Polak, Madeline; Shea, Meghan; Widick, Page; Cheng, Su-Chun; Castro, Cesar; Beumer, Jan H; Matulonis, Ursula A; Lee, Elizabeth K

Phase 1 clinical trial of the ataxia telangiectasia and Rad3-related inhibitor berzosertib with irinotecan in patients with advanced solid tumors (ETCTN 9938)

共济失调毛细血管扩张症和 Rad3 相关抑制剂 berzosertib 与伊立替康联合治疗晚期实体瘤患者的 1 期临床试验 (ETCTN 9938)

Villaruz, Liza C; Jin, Jingxiao; Wang, Hong; Lee, James J; Luke, Jason J; Rhee, John C; Waqar, Saiama N; Shapiro, Geoffrey I; Cleary, James; Davar, Diwakar; Burns, Timothy F; Verma, Rashmi; Amin, Manik; Appleman, Leonard; Ciombor, Kristen K; Davis, Elizabeth J; Riess, Jonathan W; Dees, E Claire; Kim, Edward J; Cardin, Dana; Guo, Jianxia; Christner, Susan M; Deppas, Joshua; Parise, Angelina M; Schmitz, John C; Guerrouahen, Bella S; Suchko, Michael; Contreras, Alejandro; Li, Li; Ferry-Galow, Katherine V; Chang, Ting-Chia; Jiwani, Shahanawaz; Bakkenist, Christopher J; Chu, Edward; Gore, Steven D; Beumer, Jan H

Phase Ib study of berzosertib, carboplatin, gemcitabine, and pembrolizumab in patients with squamous nonsmall lung cancer (ETCTN 10313)

一项针对鳞状非小细胞肺癌患者的berzosertib、卡铂、吉西他滨和帕博利珠单抗的Ib期研究(ETCTN 10313)

Villaruz, Liza C; Schluger, Benjamin; Wang, Hong; Ohr, James; Petro, Daniel; Fuld, Alexander D; Herzberg, Benjamin; Dawar, Richa; Nieva, Jorge; Ruiz, Jimmy; Christner, Susan M; Holleran, Julianne L; Bakkenist, Christopher J; Gore, Steven; Beumer, Jan H

Comparative in vivo toxicology of ATR inhibitors ceralasertib, elimusertib, and berzosertib alone and in combination with ionizing radiation

ATR抑制剂ceralasertib、elimusertib和berzosertib单独使用及与电离辐射联合使用时的体内毒理学比较

Deppas, Joshua J; Kiesel, Brian F; Guo, Jianxia; Rigatti, Lora H; Latoche, Joseph D; Green, Anthony; Knizner, Paul; Clump, D Andy; Pandya, Pinakin; Vendetti, Frank P; Bakkenist, Christopher J; Beumer, Jan H

The ATR Inhibitor Elimusertib in Combination with Cisplatin in Patients with Advanced Solid Tumors: A California Cancer Consortium Phase I Trial (NCI 10404)

ATR抑制剂Elimusertib联合顺铂治疗晚期实体瘤患者:加州癌症联盟I期试验(NCI 10404)

Parikh, Mamta; Uboha, Nataliya V; Takebe, Naoko; Tam, Kit; Bedard, Philippe L; Wisinski, Kari B; Mittra, Arjun; Yin, Ming; Yang, Yuanquan; Noonan, Anne M; Holleran, Julianne L; Ruel, Christopher; Frankel, Paul; Beumer, Jan H; Newman, Edward M; Danilov, Alexey V; Gore, Steven D; Lara, Primo N Jr

Association of SULT2A1 Locus With Abiraterone Clearance in the Alliance A031201: Randomized Phase III Study of Enzalutamide Compared With Enzalutamide Plus Abiraterone for Metastatic Castration-Resistant Prostate Cancer

SULT2A1基因位点与Alliance A031201研究中阿比特龙清除率的相关性:一项比较恩扎卢胺单药治疗转移性去势抵抗性前列腺癌与恩扎卢胺联合阿比特龙单药治疗的随机III期研究

Norton, Nadine; Larson, Nicholas B; Jenkins, Gregory D; Beumer, Jan H; Langevin, Brooke; Gobbaru, Jogarao; Morris, Michael J; Nakamura, Yusuke; Kroetz, Deanna L; Zhu, Hao-Jie; O'Donnell, Peter H; Lewis, Lionel D; Hertz, Daniel L

Phase 1 studies of the indenoisoquinolines LMP776 and LMP744 in patients with solid tumors and lymphomas

针对实体瘤和淋巴瘤患者的茚并异喹啉类化合物LMP776和LMP744的I期研究

O'Sullivan Coyne, Geraldine; Kummar, Shivaani; Rubinstein, Larry V; Wilsker, Deborah; Moore, Nancy; Hogu, Murielle; Piekarz, Richard; Covey, Joe; Beumer, Jan H; Ferry-Galow, Katherine V; Villaruz, Liza C; Hollingshead, Melinda G; Holleran, Julianne L; Deppas, Joshua J; Pommier, Yves; Ko, Brian; Johnson, Barry C; Parchhment, Ralph E; Ivy, Percy; Doroshow, James H; Chen, Alice P

Phase Ib study of enzalutamide with venetoclax in patients with metastatic castration-resistant prostate cancer

恩扎卢胺联合维奈托克治疗转移性去势抵抗性前列腺癌患者的Ib期研究

Perimbeti, Stuthi; Jamroze, Anmbreen; Gopalakrishnan, Dharmesh; Jain, Rohit; Jiang, Changchuan; Holleran, Julianne L; Parise, Robert A; Bies, Robert; Quinn, David; Attwood, Kristopher; Liu, Xiaozhuo; Green, Kelly; Kirk, Jason S; Beumer, Jan H; Tang, Dean G; Chatta, Gurkamal