日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

DeepTarget predicts anti-cancer mechanisms of action of small molecules by integrating drug and genetic screens

DeepTarget通过整合药物筛选和基因筛选来预测小分子抗癌作用机制。

Sinha, Sanju; Sinha, Neelam; Perales, Marlenne; Tarrab, Adi; Nguyen, Trinh; Liu, Lihe; Cantore, Thomas; Alvarez, Kyle; Patiyal, Sumeet; Mukherjee, Sumit; Madan, Sanna; Tharp, Kevin; Zhao, Jianhua; Kumar, Ranjit; Flanigan, Greg; Beutler, John A; O'Keefe, Barry R; Meerzaman, Daoud; Ben-David, Uri; Deshpande, Aniruddha J; Ruppin, Eytan

ShiftScan: A tool for rapid analysis of high-throughput differential scanning fluorimetry data and compound prioritization

ShiftScan:一种用于快速分析高通量差示扫描荧光数据和化合物优先级排序的工具

Waterworth, Samantha C; Shenoy, Shilpa R; Sharma, Nirmala D; Wolcott, Chris; Donohue, Duncan E; O'Keefe, Barry R; Beutler, John A

2-(Trihydroxyphenyl)thienopyrimidinones as Key Scaffolds for Targeting a Novel Allosteric Site of HIV-1 Integrase

2-(三羟基苯基)噻吩并嘧啶酮作为靶向HIV-1整合酶新型变构位点的关键骨架

Tocco, Graziella; Laus, Antonio; Casula, Mattia; Caboni, Pierluigi; Beutler, John A; Tramontano, Enzo; Esposito, Francesca

Sesquiterpene Coumarin Ethers and Phenylpropanoids from the Roots of Ferula drudeana, the Putative Anatolian Ecotype of the Silphion Plant

从阿魏(Ferula drudeana,可能是安纳托利亚的Silphion植物生态型)的根中分离得到的倍半萜香豆素醚和苯丙素类化合物

Kuran, Fadıl Kaan; Senadeera, Sarath P D; Wang, Dongdong; Hwang, Ji-Yeon; Goncharova, Ekaterina; Wilson, Jennifer; Wamiru, Antony; Wilson, Brice A P; Pruett, Nathanael; Du, Lin; Hoang, Chuong D; Beutler, John A; Miski, Mahmut

A Biosynthetic and Taxonomic Atlas of the Global Lichen Holobiont

全球地衣全生物体的生物合成和分类图谱

Waterworth, Samantha C; Egbert, Susan; Sorensen, John; O'Keefe, Barry R; Beutler, John A

Deconstruction of Desacetamidocolchicine's B Ring Reveals a Class 3 Atropisomeric AC Ring with Tubulin Binding Properties

去乙酰氨基秋水仙碱B环的解构揭示了一种具有微管蛋白结合特性的3类阻转异构AC环

Bejcek, Lauren P; Eli, Orugbani S; Kapkayeva, Diana M; Nafie, Jordan; Beutler, John A; Gallicchio, Emilio; Sackett, Dan L; Murelli, Ryan P

Chemoreactive 2,5-Diketopiperazines from a Penicillium sp., Structure Revision of Reported Analogues and Proposed Facile Transformation Pathways

来自青霉菌属的化学反应性2,5-二酮哌嗪类化合物、已报道类似物的结构修正及提出的简易转化途径

Khong, Quan T; Smith, Emily A; Wendt, Karen L; Dalilian, Masoumeh; Goncharova, Ekaterina I; Brownell, Isaac; Cichewicz, Robert H; Henrich, Curtis J; Beutler, John A; O'Keefe, Barry R; Du, Lin

Beyond traditional screening: Unveiling antibiotic potentials of actinomycetes in extreme environments

超越传统筛选:揭示放线菌在极端环境中的抗生素潜力

Trenozhnikova, Lyudmila P; Baimakhanova, Gul B; Baimakhanova, Baiken B; Balgimbayeva, Assya S; Daugaliyeva, Saule T; Faizulina, Elmira R; Tatarkina, Larisa G; Spankulova, Gulzhan A; Berillo, Dmitriy A; Beutler, John A

Novel Cytotoxic Sesquiterpene Coumarin Ethers and Sulfur-Containing Compounds from the Roots of Ferula turcica

从土耳其阿魏根中分离得到的新型细胞毒性倍半萜香豆素醚和含硫化合物

Eruçar, Fatma Memnune; Senadeera, Sarath P D; Wilson, Jennifer A; Goncharova, Ekaterina; Beutler, John A; Miski, Mahmut

Biological Effects of Modifications of the Englerin A Glycolate

恩格林A糖苷修饰的生物学效应

Seenadera, Sarath P D; Long, Sarah A; Akee, Rhone; Bermudez, Gabriela; Parsonage, Gregory; Strope, Jonathan; Peer, Cody; Figg, W Douglas; Parker, Kathlyn A; Beech, David J; Beutler, John A