日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hybrid reference genome assemblies for Leishmania (Viannia) braziliensis, a primary agent of mucocutaneous leishmaniasis

巴西利什曼原虫(Leishmania (Viannia) braziliensis,黏膜皮肤利什曼病的主要病原体)的混合参考基因组组装

Cotton, James A; Van den Broeck, Frederik; Myler, Peter J; Akopyants, Natalia S; Berriman, Matthew; Beverley, Stephen M

Hybrid reference genome assembly for the archetypal Leishmania (Viannia) guyanensis bearing the dsRNA totivirus LRV1

携带双链RNA托蒂病毒LRV1的典型利什曼原虫(维亚尼亚)圭亚那株的混合参考基因组组装

Myler, Peter J; Ramasamy, Gowthaman; Warren, Wesley C; Dobson, Deborah E; Beverley, Stephen M

Leishmania major surface components and DKK1 signalling via LRP6 promote migration and longevity of neutrophils in the infection site

利什曼原虫主要表面成分和DKK1通过LRP6信号通路促进中性粒细胞在感染部位的迁移和存活。

Ihedioha, Olivia C; Marcarian, Haley Q; Sivakoses, Anutr; Beverley, Stephen M; McMahon-Pratt, Diane; Bothwell, Alfred L M

Leishmania major-derived lipophosphoglycan influences the host's early immune response by inducing platelet activation and DKK1 production via TLR1/2

利什曼原虫来源的脂磷酸聚糖通过TLR1/2诱导血小板活化和DKK1产生,从而影响宿主的早期免疫反应。

Ihedioha, Olivia C; Sivakoses, Anutr; Beverley, Stephen M; McMahon-Pratt, Diane; Bothwell, Alfred L M

The sphingolipids ceramide and inositol phosphorylceramide protect the Leishmania major membrane from sterol-specific toxins

鞘脂类神经酰胺和肌醇磷酸神经酰胺保护利什曼原虫细胞膜免受甾醇特异性毒素的侵害。

Haram, Chaitanya S; Moitra, Samrat; Keane, Rilee; Kuhlmann, F Matthew; Frankfater, Cheryl; Hsu, Fong-Fu; Beverley, Stephen M; Zhang, Kai; Keyel, Peter A

Leishmania guyanensis suppressed inducible nitric oxide synthase provoked by its viral endosymbiont

圭亚那利什曼原虫抑制了由其病毒内共生体诱导的诱导型一氧化氮合酶

Kopelyanskiy, Dmitry; Desponds, Chantal; Prevel, Florence; Rossi, Matteo; Migliorini, Romain; Snäkä, Tiia; Eren, Remzi Onur; Claudinot, Stéphanie; Lye, Lon-Fye; Pasparakis, Manolis; Beverley, Stephen M; Fasel, Nicolas

Self-Hybridization in Leishmania major

利什曼原虫的自交

Ferreira, Tiago R; Inbar, Ehud; Shaik, Jahangheer; Jeffrey, Brendan M; Ghosh, Kashinath; Dobson, Deborah E; Beverley, Stephen M; Sacks, David

Use of Leishmania major parasites expressing a recombinant Trypanosoma cruzi antigen as live vaccines against Chagas disease

利用表达重组克氏锥虫抗原的利什曼原虫作为预防恰加斯病的活疫苗

Cai, Catherine W; O'Shea, Anne; Eickhoff, Christopher S; Guo, Hongjie; Lewis, Warren G; Beverley, Stephen M; Hoft, Daniel F

Inositol phosphorylceramide synthase null Leishmania are viable and virulent in animal infections where salvage of host sphingomyelin predominates

肌醇磷酸神经酰胺合成酶缺失的利什曼原虫在以宿主鞘磷脂回收利用为主的动物感染中仍能存活并具有毒性。

Kuhlmann, F Matthew; Key, Phillip N; Hickerson, Suzanne M; Turk, John; Hsu, Fong-Fu; Beverley, Stephen M

Expanded Proteomic Survey of the Human Parasite Leishmania major Focusing on Changes in Null Mutants of the Golgi GDP-Mannose/Fucose/Arabinopyranose Transporter LPG2 and of the Mitochondrial Fucosyltransferase FUT1

对人类寄生虫利什曼原虫(Leishmania major)进行扩展蛋白质组学调查,重点关注高尔基体GDP-甘露糖/岩藻糖/阿拉伯吡喃糖转运蛋白LPG2和线粒体岩藻糖基转移酶FUT1的无效突变体的变化

Polanco, Gloria; Scott, Nichollas E; Lye, Lon F; Beverley, Stephen M