DDDR-39. Untangling MEK inhibitor resistance in DMG-MAPK using coupled lineage tracing and single cell RNA sequencing
DDDR-39. 利用谱系追踪和单细胞RNA测序技术解析DMG-MAPK中的MEK抑制剂耐药机制
期刊:PLoS Genetics
影响因子:3.7
doi:10.1371/journal.pgen.1004686
Barnhoorn, Sander; Uittenboogaard, Lieneke M; Jaarsma, Dick; Vermeij, Wilbert P; Tresini, Maria; Weymaere, Michael; Menoni, Hervé; Brandt, Renata M C; de Waard, Monique C; Botter, Sander M; Sarker, Altaf H; Jaspers, Nicolaas G J; van der Horst, Gijsbertus T J; Cooper, Priscilla K; Hoeijmakers, Jan H J; van der Pluijm, Ingrid; Goni, Fernando; Wang, Ding; Suazo, Jianina; Lin, Jasmine; Okeagu, Jasmine; Gamallo‐Lana, Begonia; Mar, Adam; Wisniewski, Thomas; Venua, Rita Mari; Bissig, David Philip; Tokunaga, *Nozomi; Nakamura, Yoki; Hisaoka-Nakahsima, Kazue; Morioka, Norimitsu; Das, Molina; Grabovska, Yura; Tari, Haider; Mackay, Alan; Rogers, Rebecca; Collins, Jared; Song, Jiin; Bevington, Laura; Burford, Anna; Sejdiu, Drenusha; Beroukhim, Rameen; Bandopadhayay, Pratiti; Jones, Chris
细胞生物学
MAPK/ERK
单细胞
Sequencing
