日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A small molecule VDAC ligand inhibits ERAD and induces selective cancer cell death via disruption of calcium homeostasis.

一种小分子 VDAC 配体通过破坏钙稳态抑制 ERAD 并诱导选择性癌细胞死亡。

Yan Wenjing, Talley Daniel C, Syam Antara, Danchik Carina, Zhong Yongwang, Zhang Xianzheng, Liu Xiaoying, Baljinnyam Bolormaa, Kales Stephen C, Cyr Matthew G, Fang Yuhong, Zakharov Alexey V, Hu Xin, Niehoff Taylor, Xu Tuan, Qu Yanyan, Yang Allison, Courouble Valentine V, Yao Qin, Simeonov Anton, Huang Ruili, Rostovtseva Tatiana K, Bezrukov Sergey M, LeClair Christopher A, Egan Josephine M, Wang Hua, Tao Dingyin, Rai Ganesha, Henderson Mark J, Fang Shengyun

Logarithmic Binding and Stretched-Exponential Kinetics in Peripheral Protein Interactions with Lipid Membrane Surfaces

外周蛋白与脂质膜表面相互作用中的对数结合和拉伸指数动力学

Hoogerheide, David P; Bezrukov, Sergey M

Three mammalian VDAC isoforms distinctly regulate mitochondrial function and proteome to maintain cell metabolism.

三种哺乳动物VDAC同工型分别调节线粒体功能和蛋白质组,以维持细胞代谢。

Rajendran Megha, Rosencrans William M, Bautista Nina A, Fitzgerald Wendy, Huynh Diana, Beyene Bethel G, Quan Baiyi, Petersen Jennifer D, Hwang Julie, Chou Tsui-Fen, Bezrukov Sergey M, Rostovtseva Tatiana K

Multiple Sclerosis Drug Fingolimod Exhibits Antibacterial Activity through Bacterial Membrane Permeabilization

多发性硬化症药物芬戈莫德通过细菌膜通透性发挥抗菌活性

Syam, Antara; Rees, Benjamin; Cuervo, Sebastian; Xue, Fengtian; Sodt, Alexander; Nestorovich, Ekaterina M; Rostovtseva, Tatiana K; Bezrukov, Sergey M; Choy, John S

Antimicrobial peptide class that forms discrete β-barrel stable pores anchored by transmembrane helices.

一类抗菌肽,可形成由跨膜螺旋锚定的离散β桶状稳定孔道

Dickey Seth W, Burgin Dylan J, Antwi Ama N, Villaruz Amer, Galac Madeline R, Cheung Gordon Y C, Rostovtseva Tatiana K, Worrall Liam J, Lazarski Aleksander C, Cino Elio A, Tieleman D Peter, Bezrukov Sergey M, Strynadka Natalie C J, Otto Michael

Conformational plasticity of mitochondrial VDAC2 controls the kinetics of its interaction with cytosolic proteins

线粒体VDAC2的构象可塑性控制着其与胞质蛋白相互作用的动力学。

Rosencrans, William M; Khuntia, Harisankar; Ghahari Larimi, Motahareh; Mahalakshmi, Radhakrishnan; Yu, Tsyr-Yan; Bezrukov, Sergey M; Rostovtseva, Tatiana K

Global and local effects in lipid-mediated interactions between peripheral and integral membrane proteins

脂质介导的外周膜蛋白和整合膜蛋白之间相互作用的全局和局部效应

Rostovtseva, Tatiana K; Hoogerheide, David P; Milhizer, William A; Bezrukov, Sergey M

Particle dynamics in biconical cavities: First-passage, direct-transit, and looping time distributions

双锥腔中的粒子动力学:首达时间分布、直接穿越时间分布和环路时间分布

Berezhkovskii, Alexander M; Dagdug, Leonardo; Bezrukov, Sergey M

A Membrane-Disruptive Action of VBIT-4 Challenges Its Role as a Widely Used VDAC Oligomerization Inhibitor

VBIT-4 的膜破坏作用对其作为广泛使用的 VDAC 寡聚化抑制剂的作用提出了挑战

Ravishankar, Varun; Borges-Araújo, Luís; Lafargue, Elodie; Byrne, Deborah; Buzhinsky, Nicolas; Wolfe, Mya S; Bautista, Nina A; Beyene, Bethel G; Larimi, Motahareh G; Duneau, Jean-Pierre; Sturgis, James; Rajendran, Megha; Bezrukov, Sergey M; Casuso, Ignacio; Rostovtseva, Tatiana; Bergdoll, Lucie

Unlocking the Distinct Roles of the Three Mammalian VDAC Isoforms in Mitochondrial Respiration and Cancer Cell Metabolism.

揭示三种哺乳动物 VDAC 同工酶在细胞线粒体呼吸和癌细胞代谢中的不同作用

Rajendran Megha, Rosencrans William M, Fitzgerald Wendy, Huynh Diana, Beyene Bethel G, Quan Baiyi, Hwang Julie, Bautista Nina A, Chou Tsui-Fen, Bezrukov Sergey M, Rostovtseva Tatiana K