日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Human DNA polymerase η is regulated by mutually exclusive mono-ubiquitination and mono-NEDDylation

人类DNA聚合酶η受互斥的单泛素化和单NEDDylation修饰调控。

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkag098
Moreno, Natália C; Korchak, Emilie J; Latancia, Marcela T; D'Orlando, Dana A; Adegbenro, Temidayo; Barnes, Ryan P; Bezsonova, Irina; Woodgate, Roger; Ashton, Nicholas W
信号转导
泛素化
表观遗传
Human
发表日期：2026
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High-pH NMR to Identify Macromolecular Hydrogen-Bonds and Foldons

利用高pH值核磁共振技术鉴定大分子氢键和折叠结构

期刊:
影响因子:
doi:10.64898/2026.02.28.708709
Alexandrescu, Andrei T; Rua, Antonio J; Shah, Sameena; Fairchild, Daniel; Bezsonova, Irina
发表日期：2026
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PXL: a Nucleic Acid-Binding Module of Promyelocytic Leukemia Protein

PXL：早幼粒细胞白血病蛋白的核酸结合模块

期刊:
影响因子:
doi:10.64898/2026.02.19.706916
Fairchild, Daniel; Semenova, Irina V; Geddes-Buehre, Dane; Li, Yunfeng; Szczepaniak, Renata; Weller, Sandra K; Hao, Bing; Bezsonova, Irina
白血病
细胞生物学
粒细胞
发表日期：2026
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Activation dynamics of ubiquitin-specific protease 7

泛素特异性蛋白酶7的激活动力学

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2426632122
Valles, Gabrielle J; Korchak, Emilie J; Geddes-Buehre, Dane H; Jaiswal, Nancy; Korzhnev, Dmitry M; Bezsonova, Irina
发表日期：2025
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Functional spectrum of USP7 pathogenic variants in Hao-Fountain syndrome: Insights into the enzyme's activity, stability, and allosteric modulation

郝泉综合征中USP7致病变异的功能谱：对该酶活性、稳定性和变构调节的深入研究

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2510252122
Korchak, Emilie J; Sharafi, Mona; Jaen Maisonet, Isabella; Salazar-Chaparro, Andres; Semenova, Irina V; Khan, Hamza; O'Neil, Alison L; Caro, Pilar; Schaaf, Christian P; Buhrlage, Sara J; Bezsonova, Irina
SP7
发表日期：2025
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Small-molecule allosteric activator of ubiquitin-specific protease 7 (USP7).

泛素特异性蛋白酶 7 (USP7) 的小分子变构激活剂。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2510496122
Jaen Maisonet Isabella, Sharafi Mona, Korchak Emilie J, Salazar-Chaparro Andres, Bratt Ariana S, Parikh Tvesha, Varca Anthony C, Shah Binita, Darnowski Michael, Chung Mia, Teh Wei Pin, Che Jianwei, Bezsonova Irina, Buhrlage Sara J
SP7
发表日期：2025
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The C-terminal Tail of Ubiquitin-Specific Protease 7 Facilitates Ubiquitin Release and Ensures Efficient Catalytic Turnover

泛素特异性蛋白酶7的C端尾部促进泛素释放并确保高效的催化周转

期刊:Journal of Molecular Biology
影响因子:4.5
doi:10.1016/j.jmb.2025.169298
Korchak, Emilie J; Geddes-Buehre, Dane H; Bezsonova, Irina
发表日期：2025
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Functional Spectrum of USP7 Pathogenic Variants in Hao-Fountain Syndrome: Insights into the Enzyme's Activity, Stability, and Allosteric Modulation

郝泉综合征中USP7致病变异的功能谱：对该酶的活性、稳定性和变构调节的深入了解

期刊:
影响因子:
doi:10.1101/2025.03.20.644318
Korchak, Emilie J; Sharafi, Mona; Maisonet, Isabella Jaen; Caro, Pilar; Schaaf, Christian P; Buhrlage, Sara J; Bezsonova, Irina
SP7
发表日期：2025
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DNA polymerase η is regulated by mutually exclusive mono-ubiquitination and mono-NEDDylation.

DNA聚合酶η受互斥的单泛素化和单NEDDylation调控

期刊:
影响因子:
doi:10.1101/2024.10.12.618026
Moreno Natália Cestari, Korchak Emilie J, Latancia Marcela Teatin, D'Orlando Dana A, Adegbenro Temidayo, Bezsonova Irina, Woodgate Roger, Ashton Nicholas W
表观遗传
泛素化
发表日期：2024
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Conformational exchange at a C(2)H(2) zinc-binding site facilitates redox sensing by the PML protein.

C(2)H(2)锌结合位点的构象交换促进了PML蛋白的氧化还原感知

期刊:Structure
影响因子:4.3
doi:10.1016/j.str.2023.06.014
Bregnard Thomas A, Fairchild Daniel, Erlandsen Heidi, Semenova Irina V, Szczepaniak Renata, Ahmed Affrin, Weller Sandra K, Korzhnev Dmitry M, Bezsonova Irina
其它
发表日期：2023
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