日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Synthesis and characterization of [76Br]-labeled high-affinity A3 adenosine receptor ligands for positron emission tomography

合成和表征[76Br]标记的高亲和力A3腺苷受体配体用于正电子发射断层扫描

Kiesewetter, Dale O; Lang, Lixin; Ma, Ying; Bhattacharjee, Abesh Kumar; Gao, Zhan-Guo; Joshi, Bhalchandra V; Melman, Artem; de Castro, Sonia; Jacobson, Kenneth A

Synthesis and pharmacological characterization of [(125)I]MRS1898, a high-affinity, selective radioligand for the rat A(3) adenosine receptor

合成并表征了[(125)I]MRS1898,一种对大鼠A(3)腺苷受体具有高亲和力和选择性的放射性配体。

Gao, Zhan-Guo; Teng, Bao; Wu, Haitao; Joshi, Bhalchandra V; Griffiths, Gary L; Jacobson, Kenneth A

Synthesis and P2Y receptor activity of nucleoside 5'-phosphonate derivatives

核苷5'-膦酸酯衍生物的合成及其P2Y受体活性

Cosyn, Liesbet; Van Calenbergh, Serge; Joshi, Bhalchandra V; Ko, Hyojin; Carter, Rhonda L; Kendall Harden, T; Jacobson, Kenneth A

Synthesis and structure-activity relationship studies of tyrosine-based antagonists at the human P2X7 receptor

人P2X7受体酪氨酸类拮抗剂的合成及构效关系研究

Lee, Ga Eun; Joshi, Bhalchandra V; Chen, Wangzhong; Jeong, Lak Shin; Moon, Hyung Ryong; Jacobson, Kenneth A; Kim, Yong-Chul

UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis

UDP作用于P2Y6受体是小胶质细胞吞噬作用的介质。

Koizumi, Schuichi; Shigemoto-Mogami, Yukari; Nasu-Tada, Kaoru; Shinozaki, Yoichi; Ohsawa, Keiko; Tsuda, Makoto; Joshi, Bhalchandra V; Jacobson, Kenneth A; Kohsaka, Shinichi; Inoue, Kazuhide

P2X purinergic receptor-mediated ionic current in cardiac myocytes of calsequestrin model of cardiomyopathy: implications for the treatment of heart failure

钙调蛋白心肌病模型中心肌细胞中 P2X 嘌呤受体介导的离子电流:对心力衰竭治疗的意义

Jian-Bing Shen, Chunxia Cronin, Dmitry Sonin, Bhalchandra V Joshi, Maria Gongora Nieto, David Harrison, Kenneth A Jacobson, Bruce T Liang

Positive inotropic effects by uridine triphosphate (UTP) and uridine diphosphate (UDP) via P2Y2 and P2Y6 receptors on cardiomyocytes and release of UTP in man during myocardial infarction

尿苷三磷酸(UTP)和尿苷二磷酸(UDP)通过P2Y2和P2Y6受体对心肌细胞产生正性肌力作用,以及心肌梗死期间UTP在人体内的释放

Wihlborg, Anna-Karin; Balogh, Johanna; Wang, Lingwei; Borna, Catharina; Dou, Ying; Joshi, Bhalchandra V; Lazarowski, Eduardo; Jacobson, Kenneth A; Arner, Anders; Erlinge, David

Conversion of A3 adenosine receptor agonists into selective antagonists by modification of the 5'-ribofuran-uronamide moiety

通过修饰 5'-核糖呋喃-尿酰胺部分将 A3 腺苷受体激动剂转化为选择性拮抗剂

Gao, Zhan-Guo; Joshi, Bhalchandra V; Klutz, Athena M; Kim, Soo-Kyung; Lee, Hyuk Woo; Kim, Hea Ok; Jeong, Lak Shin; Jacobson, Kenneth A

Action of nucleosides and nucleotides at 7 transmembrane-spanning receptors

核苷和核苷酸在7次跨膜受体上的作用

Jacobson, Kenneth A; Costanzi, Stefano; Kim, Soo-Kyung; Roh, Eunjoo; Joshi, Bhalchandra V; Tchilibon, Susanna; Duong, Heng T; Gao, Zhan-Guo

NUCLEOSIDE PRODRUGS OF A(3) ADENOSINE RECEPTOR AGONISTS AND ANTAGONISTS

α(3)腺苷受体激动剂和拮抗剂的核苷前药

Besada, Pedro; Mamedova, Liaman K; Palaniappan, Krishnan K; Gao, Zhan-Guo; Joshi, Bhalchandra V; Jeong, Lak Shin; Civan, Mortimer M; Jacobson, Kenneth A