Bhandari Nilam相关文献与解析，生知库 | 链接生命科学的每一步

FDA-approved drug library screen identifies antidepressants, antimicrobials, anti-COPD, and anti-CVD agents as blockers of NLRP3 inflammasome and sepsis in a sex-dependent manner

FDA批准的药物库筛选发现，抗抑郁药、抗菌药、抗慢性阻塞性肺病（COPD）药物和抗心血管疾病（CVD）药物能够以性别依赖的方式阻断NLRP3炎症小体并导致脓毒症。

doi:10.64898/2026.03.05.709979

Timinski, Kara; Neupane, Kalash; Prince, Ashutosh; Bhandari, Nilam; Khan, Mariam R; Sharma, Swati; Shiravand, Yavar; Traughber, C Alicia; Raquepaw, Zackery; Gulshan, Kailash

ATP8B1 regulates PIP2 localization and cleavage of pyroptotic executioner Gasdermin D.

ATP8B1 调节 PIP2 定位和焦亡执行者 Gasdermin D 的切割

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2502798122

Bhandari Nilam, Prince Ashutosh, Khan Mariam R, Traughber C Alicia, Neupane Kalash, Lorkowski Shuhui W, Brubaker Gregory, Ertugral Elif G, Kothapalli Chandrasekhar R, Dubyak George R, Smith Jonathan D, Gulshan Kailash

焦亡

发表日期：2025

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Enigmatic functions of ATP8B1: cholestasis, inflammation, phosphoinositide flipping, and cellular homeostasis

ATP8B1 的神秘功能：胆汁淤积、炎症、磷脂酰肌醇翻转和细胞稳态

期刊:Cell Cycle

影响因子:3.4

doi:10.1080/15384101.2025.2574275

Prince, Ashutosh; Traughber, C Alicia; Shiravand, Yavar; Bhandari, Nilam; Khan, Mariam R; Sharma, Swati; Timinski, Kara; Murray, Karen F; Bull, Laura N; Gulshan, Kailash

Disulfiram reduces atherosclerosis and enhances efferocytosis, autophagy, and atheroprotective gut microbiota in hyperlipidemic mice

双硫仑可减轻高脂血症小鼠的动脉粥样硬化，并增强胞吞作用、自噬作用和抗动脉粥样硬化肠道菌群。

期刊:

影响因子:

doi:10.1101/2023.10.17.562757

Traughber, C Alicia; Timinski, Kara; Prince, Ashutosh; Bhandari, Nilam; Neupane, Kalash; Khan, Mariam R; Opoku, Esther; Opoku, Emmanuel; Brubaker, Gregory; Nageshwar, Kanuri; Ertugral, Elif G; Naggareddy, Prabha; Kothapalli, Chandrasekhar R; Smith, Jonathan D; Gulshan, Kailash

Antibiotics Use Patterns in Low- and Middle-Income Countries: A Systematic Review Analysis

中低收入国家抗生素使用模式：系统性综述分析

FDA-approved drug library screen identifies antidepressants, antimicrobials, anti-COPD, and anti-CVD agents as blockers of NLRP3 inflammasome and sepsis in a sex-dependent manner

FDA批准的药物库筛选发现，抗抑郁药、抗菌药、抗慢性阻塞性肺病（COPD）药物和抗心血管疾病（CVD）药物能够以性别依赖的方式阻断NLRP3炎症小体并导致脓毒症。

ATP8B1 regulates PIP2 localization and cleavage of pyroptotic executioner Gasdermin D.

ATP8B1 调节 PIP2 定位和焦亡执行者 Gasdermin D 的切割

Enigmatic functions of ATP8B1: cholestasis, inflammation, phosphoinositide flipping, and cellular homeostasis

ATP8B1 的神秘功能：胆汁淤积、炎症、磷脂酰肌醇翻转和细胞稳态

Disulfiram reduces atherosclerosis and enhances efferocytosis, autophagy, and atheroprotective gut microbiota in hyperlipidemic mice

双硫仑可减轻高脂血症小鼠的动脉粥样硬化，并增强胞吞作用、自噬作用和抗动脉粥样硬化肠道菌群。