日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A tumor-promoting inflammatory SPP1+ macrophage-IL-6-CRP axis drives immune dysfunction in bladder cancer

肿瘤促进性炎症SPP1+巨噬细胞-IL-6-CRP轴驱动膀胱癌免疫功能障碍

Tran, Michelle A; Cho, Byuri Angela; Izadmehr, Sudeh; Yoo, Seong-Keun; Youssef, Dina; Anker, Jonathan F; Farkas, Adam M; Figueiredo, Igor; Lee, Karen; Ananthanarayanan, Aparna; Balan, Sreekumar; Onkar, Sayali; Banchereau, Romain; Gupta, Saurabh; Chhibber, Aparna; Wang, Li; Beaumont, Kristin G; Li, Ziao; Garcia-Barros, Monica; Bicak, Mesude; Cordon-Cardo, Carlos; Brody, Rachel; Kim-Schulze, Seunghee; Yuen, Kobe; Mariathasan, Sanjeev; Atiq, Saad O; Adeyelu, Tolulope T; Elliott, Andrew; Barata, Pedro; McKay, Rana R; Gnjatic, Sacha; Gonzalez-Kozlova, Edgar; Mehrazin, Reza; Horowitz, Amir; Sfakianos, John P; Chowell, Diego; Galsky, Matthew D; Bhardwaj, Nina

Pipe dream to pipeline: Journey of cancer vaccines and the road ahead

从梦想到实际应用:癌症疫苗的研发历程及未来之路

Onkar, Sayali; Bozkus, Cansu Cimen; Saxena, Mansi; Bhardwaj, Nina

Improving peptide vaccine manufacturability without sacrificing immunogenicity: substitution of methionine and cysteine with oxidation-resistant isosteres

在不牺牲免疫原性的前提下提高肽疫苗的生产性能:用抗氧化同排体替代甲硫氨酸和半胱氨酸

Ishizuka, Andrew S; Garliss, Christopher M; Goddu, Robert N; Merolle, Maria; Schrager, Alec; Ramirez-Valdez, Andrei; Ren, Qiuyin; Baharom, Faezzah; Essandoh, Matthew; Palacorolla, Nicholas G; Finnigan, John P; Douek, Daniel C; Bhardwaj, Nina; Seder, Robert A; Lynn, Geoffrey M; Wilson, David R

Prediction of checkpoint inhibitor immunotherapy efficacy for cancer using routine blood tests and clinical data

利用常规血液检查和临床数据预测癌症免疫检查点抑制剂疗法的疗效

Yoo, Seong-Keun; Fitzgerald, Conall W; Cho, Byuri Angela; Fitzgerald, Bailey G; Han, Catherine; Koh, Elizabeth S; Pandey, Abhinav; Sfreddo, Hannah; Crowley, Fionnuala; Korostin, Michelle Rudshteyn; Debnath, Neha; Leyfman, Yan; Valero, Cristina; Lee, Mark; Vos, Joris L; Lee, Andrew Sangho; Zhao, Karena; Lam, Stanley; Olumuyide, Ezekiel; Kuo, Fengshen; Wilson, Eric A; Hamon, Pauline; Hennequin, Clotilde; Saffern, Miriam; Vuong, Lynda; Hakimi, A Ari; Brown, Brian; Merad, Miriam; Gnjatic, Sacha; Bhardwaj, Nina; Galsky, Matthew D; Schadt, Eric E; Samstein, Robert M; Marron, Thomas U; Gönen, Mithat; Morris, Luc G T; Chowell, Diego

mTOR inhibition modulates vaccine-induced immune responses to generate memory T cells in patients with solid tumors

mTOR抑制剂可调节疫苗诱导的免疫反应,从而在实体瘤患者中产生记忆性T细胞。

Withers, Henry G; Matsuzaki, Junko; Long, Mark; Rosario, Spencer R; Chodon, Thinle; Tsuji, Takemasa; Koya, Richard; Yan, Li; Wang, Jianming; Keler, Tibor; Lele, Shashikant B; Zsiros, Emese; Lugade, Amit; Hutson, Alan; Blank, Stephanie; Bhardwaj, Nina; Shrikant, Protul; Liu, Song; Odunsi, Kunle

Clinical and Translational Results from PORTER, a Multicohort Phase I Platform Trial of Combination Immunotherapy in Metastatic Castration-Resistant Prostate Cancer

PORTER研究的临床和转化结果:一项针对转移性去势抵抗性前列腺癌的联合免疫疗法多队列I期平台试验

Galsky, Matthew D; Autio, Karen A; Cabanski, Christopher R; Wentzel, Kristopher; Graff, Julie N; Friedlander, Terence W; Howes, Timothy R; Shotts, Kristin M; Densmore, Julie; Spasic, Marko; Da Silva, Diane M; Chen, Richard O; Lata, Jennifer; Skolnik, Jeffrey; Keler, Tibor; Yellin, Michael J; LaVallee, Theresa M; Fairchild, Justin; Boffo, Silvia; O'Donnell-Tormey, Jill; Dugan, Ute; Bhardwaj, Nina; Subudhi, Sumit K; Fong, Lawrence

Targeting neoantigens conserved across organs and species overcomes tumor immune escape

靶向跨器官和跨物种保守的新抗原可以克服肿瘤免疫逃逸。

Mestrallet, Guillaume; Ward, Ross W; Brown, Matthew; Boumelha, Jesse; Rentzeperis, Frederika; Vaninov, Natalie; Saffern, Miriam; Olumuyide, Ezekiel; Suri, Prerna; Balan, Sreekumar; Velazquez, Leandra; Ananthanarayanan, Aparna; Chen, Zhihong; Lucas, Aimee L; Merad, Miriam; Bozkus, Cansu Cimen; Vabret, Nicolas; Samstein, Robert M; Bhardwaj, Nina

T cell epitope mapping reveals immunodominance of evolutionarily conserved regions within SARS-CoV-2 proteome

T细胞表位定位揭示了SARS-CoV-2蛋白质组中进化保守区域的免疫优势

Bozkus, Cansu Cimen; Brown, Matthew; Velazquez, Leandra; Thomas, Marcus; Wilson, Eric A; O'Donnell, Timothy; Ruchnewitz, Denis; Geertz, Douglas; Bykov, Yonina; Kodysh, Julia; Oguntuyo, Kasopefoluwa Y; Roudko, Vladimir; Hoyos, David; Srivastava, Komal D; Kleiner, Giulio; Alshammary, Hala; Karekar, Neha; McClain, Christopher; Gopal, Ramya; Nie, Kai; Del Valle, Diane; Delbeau-Zagelbaum, Daniela; Rodriguez, Denise; Setal, Jessica; Carroll, Emily; Wiesendanger, Margrit; Gulko, Percio S; Charney, Alexander; Merad, Miriam; Kim-Schulze, Seunghee; Lee, Benhur; Wajnberg, Ania; Simon, Viviana; Greenbaum, Benjamin D; Chowell, Diego; Vabret, Nicolas; Luksza, Marta; Bhardwaj, Nina

Cancer Immunotherapy Trials Network 12: Pembrolizumab in HIV-Associated Kaposi Sarcoma

癌症免疫疗法试验网络 12:帕博利珠单抗治疗 HIV 相关卡波西肉瘤

Lurain, Kathryn; Ramaswami, Ramya; Ekwede, Irene; Eulo, Vanessa; Goyal, Gaurav; Menon, Manoj; Odeny, Thomas A; Sharon, Elad; Wagner, Michael J; Wang, Chia-Ching Jackie; Bhardwaj, Nina; Friedlander, Philip A; Abdul-Hay, Maher; Cornejo Castro, Elena M; Labo, Nazzarena; Marshall, Vickie Ann; Miley, Wendell; Moore, Kyle; Roshan, Romin; Whitby, Denise; Kask, Angela Shaulov; Kaiser, Judith; Han, Emma; Wright, Anna; Yarchoan, Robert; Fling, Steven P; Uldrick, Thomas S

Coordinated macrophage and T cell interactions mediate response to checkpoint blockade in colorectal cancer.

巨噬细胞和 T 细胞的协同相互作用介导结直肠癌对检查点阻断的反应

Mestrallet Guillaume, Brown Matthew, Vaninov Natalie, Cho Nam Woo, Velazquez Leandra, Ananthanarayanan Aparna, Spitzer Matthew, Vabret Nicolas, Bozkus Cansu Cimen, Samstein Robert M, Bhardwaj Nina