日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Innovative approach to support therapeutic proteins' similarity in hydrodynamic size using high-throughput dynamic light scattering and forced degradation

利用高通量动态光散射和强制降解技术,创新性地研究治疗性蛋白质在流体动力学尺寸上的相似性

Bhirde, Ashwinkumar; Harish, Siri; Trunfio, Nicholas; de Luna, Isabella F; Smith, William; Fu, Qiong

Root cause analysis investigation of visible particulates in therapeutic protein drug products using morphologically directed Raman spectroscopy

利用形态学导向拉曼光谱法对治疗性蛋白质药物产品中可见颗粒物进行根本原因分析

de Luna, Isabella F; Telikepalli, Srivalli N; Carrier, Michael; Ripple, Dean; Srinivasan, Charudharshini; O'Connor, Thomas; Lute, Scott; Bhirde, Ashwinkumar

Morphologically-Directed Raman Spectroscopy as an Analytical Method for Subvisible Particle Characterization in Therapeutic Protein Product Quality

形态导向拉曼光谱法作为治疗性蛋白产品质量中亚可见颗粒表征的分析方法

Kim, Minkyung; Ma, Youlong; Srinivasan, Charudharshini; O'Connor, Thomas; Telikepalli, Srivalli N; Ripple, Dean C; Lute, Scott; Bhirde, Ashwinkumar

An Interlaboratory Comparison on the Characterization of a Sub-micrometer Polydisperse Particle Dispersion

亚微米多分散粒子分散性表征的实验室间比较

Kurt D Benkstein, Gurusamy Balakrishnan, Ashwinkumar Bhirde, Pascal Chalus, Tapan K Das, Ngoc Do, David L Duewer, Nazar Filonov, Fook Chiong Cheong, Patrick Garidel, Nicole S Gill, Adam D Grabarek, David G Grier, Judith Hadley, Andrew D Hollingsworth, Wesley W Howard, Maciej Jarzębski, Wim Jiskoot, 

The ELISA Detectability and Potency of Pegfilgrastim Decrease in Physiological Conditions: Key Roles for Aggregation and Individual Variability

生理状况下培非格司亭的 ELISA 检测能力和效力下降:聚集和个体差异的关键作用

Tao Xie, Hui Fang, Weiming Ouyang, Phillip Angart, Meng-Jung Chiang, Ashwinkumar A Bhirde, Faruk Sheikh, Patrick Lynch, Ankit B Shah, Sharadrao M Patil, Kang Chen, Meiyu Shen, Cyrus Agarabi, Raymond P Donnelly, Kurt Brorson, Sarah J Schrieber, Kristina E Howard, Sarah M Rogstad, David M Frucht

Targeted therapeutic nanotubes influence the viscoelasticity of cancer cells to overcome drug resistance

靶向治疗纳米管通过影响癌细胞的粘弹性来克服耐药性。

Bhirde, Ashwinkumar A; Chikkaveeraiah, Bhaskara V; Srivatsan, Avinash; Niu, Gang; Jin, Albert J; Kapoor, Ankur; Wang, Zhe; Patel, Sachin; Patel, Vyomesh; Gorbach, Alexander M; Leapman, Richard D; Gutkind, J Silvio; Hight Walker, Angela R; Chen, Xiaoyuan

Photosensitizer loaded nano-graphene for multimodality imaging guided tumor photodynamic therapy

用于多模态成像引导肿瘤光动力疗法的光敏剂负载纳米石墨烯

Rong, Pengfei; Yang, Kai; Srivastan, Avinash; Kiesewetter, Dale O; Yue, Xuyi; Wang, Fu; Nie, Liming; Bhirde, Ashwinkumar; Wang, Zhe; Liu, Zhuang; Niu, Gang; Wang, Wei; Chen, Xiaoyuan

Multiplex imaging of an intracellular proteolytic cascade by using a broad-spectrum nanoquencher

利用广谱纳米猝灭剂对细胞内蛋白水解级联反应进行多重成像

Huang, Xinglu; Swierczewska, Magdalena; Choi, Ki Young; Zhu, Lei; Bhirde, Ashwinkumar; Park, Jinwoo; Kim, Kwangmeyung; Xie, Jin; Niu, Gang; Lee, Kang Choon; Lee, Seulki; Chen, Xiaoyuan

Sticky nanoparticles: a platform for siRNA delivery by a bis(zinc(II) dipicolylamine)-functionalized, self-assembled nanoconjugate

粘性纳米颗粒:一种通过双(锌(II)二吡啶胺)功能化的自组装纳米缀合物递送siRNA的平台

Liu, Gang; Choi, Ki Young; Bhirde, Ashwinkumar; Swierczewska, Magdalena; Yin, Juan; Lee, Sang Wook; Park, Jae Hyung; Hong, Jong In; Xie, Jin; Niu, Gang; Kiesewetter, Dale O; Lee, Seulki; Chen, Xiaoyuan

Nuclear mapping of nanodrug delivery systems in dynamic cellular environments

在动态细胞环境中对纳米药物递送系统进行核定位

Bhirde, Ashwinkumar A; Kapoor, Ankur; Liu, Gang; Iglesias-Bartolome, Ramiro; Jin, Albert; Zhang, Guofeng; Xing, Ruijun; Lee, Seulki; Leapman, Richard D; Gutkind, J Silvio; Chen, Xiaoyuan