日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CRISPR screens in the context of immune selection identify CHD1 and MAP3K7 as mediators of cancer immunotherapy resistance.

在免疫选择的背景下,CRISPR 筛选发现 CHD1 和 MAP3K7 是癌症免疫疗法耐药性的介质。

Watterson Alex, Picco Gabriele, Veninga Vivien, Samarakoon Youhani, Cattaneo Chiara M, Vieira Sara F, Karakoc Emre, Bhosle Shriram, Battaglia Thomas W, Consonni Sarah, Halim Timotheus Y F, Voest Emile E, Garnett Mathew J, Coelho Matthew A

Somatic mutation rates scale with lifespan across mammals

哺乳动物的体细胞突变率随寿命而变化。

Cagan, Alex; Baez-Ortega, Adrian; Brzozowska, Natalia; Abascal, Federico; Coorens, Tim H H; Sanders, Mathijs A; Lawson, Andrew R J; Harvey, Luke M R; Bhosle, Shriram; Jones, David; Alcantara, Raul E; Butler, Timothy M; Hooks, Yvette; Roberts, Kirsty; Anderson, Elizabeth; Lunn, Sharna; Flach, Edmund; Spiro, Simon; Januszczak, Inez; Wrigglesworth, Ethan; Jenkins, Hannah; Dallas, Tilly; Masters, Nic; Perkins, Matthew W; Deaville, Robert; Druce, Megan; Bogeska, Ruzhica; Milsom, Michael D; Neumann, Björn; Gorman, Frank; Constantino-Casas, Fernando; Peachey, Laura; Bochynska, Diana; Smith, Ewan St John; Gerstung, Moritz; Campbell, Peter J; Murchison, Elizabeth P; Stratton, Michael R; Martincorena, Iñigo

A suspension technique for efficient large-scale cancer organoid culturing and perturbation screens

用于高效大规模癌症类器官培养和扰动筛选的悬浮技术

Price, Stacey; Bhosle, Shriram; Gonçalves, Emanuel; Li, Xiaodun; McClurg, Dylan P; Barthorpe, Syd; Beck, Alex; Hall, Caitlin; Lightfoot, Howard; Farrow, Luke; Ansari, Rizwan; Jackson, David A; Allen, Laura; Roberts, Kirsty; Beaver, Charlotte; Francies, Hayley E; Garnett, Mathew J

Integration of transcriptional and mutational data simplifies the stratification of peripheral T-cell lymphoma

转录组和突变数据的整合简化了外周T细胞淋巴瘤的分层

Maura, Francesco; Agnelli, Luca; Leongamornlert, Daniel; Bolli, Niccolò; Chan, Wing C; Dodero, Anna; Carniti, Cristiana; Heavican, Tayla B; Pellegrinelli, Alessio; Pruneri, Giancarlo; Butler, Adam; Bhosle, Shriram G; Chiappella, Annalisa; Di Rocco, Alice; Zinzani, Pier Luigi; Zaja, Francesco; Piva, Roberto; Inghirami, Giorgio; Wang, Wenyi; Palomero, Teresa; Iqbal, Javeed; Neri, Antonino; Campbell, Peter J; Corradini, Paolo

Unsupervised correction of gene-independent cell responses to CRISPR-Cas9 targeting

对 CRISPR-Cas9 靶向治疗中基因非依赖性细胞反应的非监督式校正

Iorio, Francesco; Behan, Fiona M; Gonçalves, Emanuel; Bhosle, Shriram G; Chen, Elisabeth; Shepherd, Rebecca; Beaver, Charlotte; Ansari, Rizwan; Pooley, Rachel; Wilkinson, Piers; Harper, Sarah; Butler, Adam P; Stronach, Euan A; Saez-Rodriguez, Julio; Yusa, Kosuke; Garnett, Mathew J

Resequencing the susceptibility gene, ITGAM, identifies two functionally deleterious rare variants in systemic lupus erythematosus cases.

对易感基因 ITGAM 进行重新测序,发现系统性红斑狼疮病例中存在两种功能有害的罕见变异

Roberts Amy L, Thomas Ellen Ra, Bhosle Shriram, Game Laurence, Obraztsova Olga, Aitman Timothy J, Vyse Timothy J, Rhodes Benjamin

CEP: a conformational epitope prediction server

CEP:构象表位预测服务器

Kulkarni-Kale, Urmila; Bhosle, Shriram; Kolaskar, A S

VirGen: a comprehensive viral genome resource

VirGen:一个全面的病毒基因组资源

Kulkarni-Kale, Urmila; Bhosle, Shriram; Manjari, G Sunitha; Kolaskar, A S