日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Large-scale integration of omics and electronic health records to identify potential risk protein biomarkers and therapeutic drugs for cancer prevention

大规模整合组学和电子健康记录,以识别潜在的风险蛋白生物标志物和癌症预防治疗药物

Li, Qing; Song, Qingyuan; Chen, Zhishan; Choi, Jungyoon; Moreno, Victor; Ping, Jie; Wen, Wanqing; Li, Chao; Shu, Xiang; Yan, Jun; Shu, Xiao-Ou; Cai, Qiuyin; Long, Jirong; Huyghe, Jeroen R; Pai, Rish; Gruber, Stephen B; Yang, Yaohua; Casey, Graham; Wang, Xusheng; Toriola, Adetunji T; Li, Li; Singh, Bhuminder; Lau, Ken S; Zhou, Li; Zhang, Zichen; Wu, Chong; Peters, Ulrike; Zheng, Wei; Long, Quan; Yin, Zhijun; Guo, Xingyi

Protocol for high-throughput drug screening in 384-well 3D collagen cultures of SC colorectal cancer cells using colony morphology as a readout

利用集落形态作为读数指标,在384孔3D胶原培养的SC结直肠癌细胞中进行高通量药物筛选的方案

Harmych, Sarah J; Hasaka, Thomas P; Jones, Vivian Truong; Bauer, Joshua A; Singh, Bhuminder

3D collagen high-throughput screen identifies drugs that induce epithelial polarity and enhance chemotherapy response in colorectal cancer.

3D胶原蛋白高通量筛选可识别诱导上皮极性并增强结直肠癌化疗反应的药物

Harmych Sarah J, Hasaka Thomas P, Sievers Chelsie K, Kang Seung Woo, Ramirez Marisol A, Jones Vivian Truong, Zhao Zhiguo, Kovtun Oleg, Wahoski Claudia C, Liu Qi, Lau Ken S, Coffey Robert J, Bauer Joshua A, Singh Bhuminder

Metabolic Response to Small Molecule Therapy in Colorectal Cancer Tracked with Raman Spectroscopy and Metabolomics

利用拉曼光谱和代谢组学追踪结直肠癌小分子疗法的代谢反应

Cutshaw, Gabriel; Joshi, Neeraj; Wen, Xiaona; Quam, Elizabeth; Bogatcheva, Galina; Hassan, Nora; Uthaman, Saji; Waite, Joshua; Sarkar, Soumik; Singh, Bhuminder; Bardhan, Rizia

Inhibition of autocrine HGF maturation overcomes cetuximab resistance in colorectal cancer

抑制自分泌HGF成熟可克服结直肠癌的西妥昔单抗耐药性

Vivian Truong Jones # ,Ramona Graves-Deal # ,Zheng Cao ,Galina Bogatcheva ,Marisol A Ramirez ,Sarah J Harmych ,James N Higginbotham ,Vineeta Sharma ,Vishnu C Damalanka ,Claudia C Wahoski ,Neeraj Joshi ,Maria Johnson Irudayam ,Joseph T Roland ,Gregory D Ayers ,Qi Liu ,Robert J Coffey ,James W Janetka ,Bhuminder Singh

Analysis of EGFR binding hotspots for design of new EGFR inhibitory biologics

分析EGFR结合热点以设计新型EGFR抑制性生物制剂

Tydings, Claiborne W; Singh, Bhuminder; Smith, Adam W; Ledwitch, Kaitlyn V; Brown, Benjamin P; Lovly, Christine M; Walker, Allison S; Meiler, Jens

The Roles of RAC1 and RAC1B in Colorectal Cancer and Their Potential Contribution to Cetuximab Resistance

RAC1和RAC1B在结直肠癌中的作用及其对西妥昔单抗耐药性的潜在贡献

Wahoski, Claudia C; Singh, Bhuminder

Sequence and structural insights of monoleucine-based sorting motifs contained within the cytoplasmic domains of basolateral proteins

基底外侧蛋白胞质结构域中单亮氨酸基分选基序的序列和结构解析

Harmych, Sarah J; Tydings, Claiborne W; Meiler, Jens; Singh, Bhuminder

The room where it happens: addressing diversity, equity, and inclusion in National Clinical Trials Network clinical trial leadership

关键所在:探讨国家临床试验网络临床试验领导层的多样性、公平性和包容性问题

Snyder, Rebecca A; Burtness, Barbara; Cho, May; Del Rivero, Jaydira; Doroshow, Deborah B; Hitchcock, Kathryn E; Kalyan, Aparna; Kim, Christina A; Lukovic, Jelena; Parikh, Aparna R; Sanford, Nina N; Singh, Bhuminder; Shen, Chan; Shroff, Rachna T; Vijayvergia, Namrata; Goodman, Karyn A; Kunz, Pamela L

Monitoring Metabolic Changes in Response to Chemotherapies in Cancer with Raman Spectroscopy and Metabolomics

利用拉曼光谱和代谢组学监测癌症化疗引起的代谢变化

Cutshaw, Gabriel; Hassan, Nora; Uthaman, Saji; Wen, Xiaona; Singh, Bhuminder; Sarkar, Anwesha; Bardhan, Rizia